Hotels near Lowcountry Estuarium

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 25 - Dec 26
Tomorrow
Dec 26 - Dec 27
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lowcountry Estuarium hotels

Miscellaneous
Super 8 by Wyndham Port Royal/Beaufort

Super 8 by Wyndham Port Royal/Beaufort

Super 8 by Wyndham Port Royal/Beaufort
2.0 star property
2.3 km from Lowcountry Estuarium
6.0 out of 10, (907)
"The room could have been a little cleaner but all and all it was Great! "
United States
Gina
The price is P3,502
P3,852 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Super 8 by Wyndham Port Royal/Beaufort
Exterior
Best Western Sea Island Inn

Best Western Sea Island Inn

Best Western Sea Island Inn
2.5 star property
6.1 km from Lowcountry Estuarium
9.4 out of 10, Exceptional, (1000)
"Perfect spot!"
United States
Tricia
The price is P8,739
P9,613 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Sea Island Inn
Premium bedding, individually decorated, individually furnished
Beaufort Inn

Beaufort Inn

Beaufort Inn
3.5 star property
6.2 km from Lowcountry Estuarium
9.0 out of 10, Wonderful, (1000)
"The staff were friendly and the cottage room was clean and comfortable. "
United States
Samantha
Beaufort Inn
View from property
City Loft Hotel

City Loft Hotel

City Loft Hotel
3.5 star property
6.2 km from Lowcountry Estuarium
9.4 out of 10, Exceptional, (759)
"Great place to stay in city center Beaufort. Easy free parking, friendly staff, comfy mattresses, nice bathroom and shower. Location was perfect for walking to shops and restaurants."
United States
Laura
The price is P8,383
P9,222 total
includes taxes & fees
Dec 28 - Dec 29
City Loft Hotel
Egyptian cotton sheets, premium bedding, pillowtop beds
The Emerald Boutique Stays

The Emerald Boutique Stays

The Emerald Boutique Stays
2.5 star property
6.4 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (221)
"Close to downtown shopping and restaurants. Nice room and helpful staff."
United States
Jeffrey
The price is P7,576
P8,334 total
includes taxes & fees
Dec 31 - Jan 1, 2026
The Emerald Boutique Stays
Exterior
607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort
2.5 star property
6.2 km from Lowcountry Estuarium
9.6 out of 10, Exceptional, (90)
"Great Inn! Location, view, cleanliness, friendly staff!"
United States
Nicole
607 Bay Inn Downtown Beaufort
Exterior
Rhett House Inn

Rhett House Inn

Rhett House Inn
4.0 star property
6.2 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (643)
"What a lovely stay. Beautiful, clean and friendly staff made this stay wonderful. Will stay again while in Beaufort."
United States
REBECCA
The price is P8,557
P11,295 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Rhett House Inn
Porch
Circa 1785

Circa 1785

Circa 1785
4.0 star property
6.9 km from Lowcountry Estuarium
9.6 out of 10, Exceptional, (137)
"Our room (#4) was FABULOUS. Huge with great bathroom and comfy bed and linens. Did not want to leave. 😫"
United States
Jill
The price is P7,559
P8,315 total
includes taxes & fees
Dec 28 - Dec 29
Circa 1785
Balcony
Anchorage 1770

Anchorage 1770

Anchorage 1770
5.0 star property
6.2 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (219)
"Great property at a wonderful location."
United States
Dave
Anchorage 1770
Snack bar
Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC
2.5 star property
7.5 km from Lowcountry Estuarium
9.0 out of 10, Wonderful, (712)
"Awesome stay!!!"
United States
Michael
The price is P5,501
P6,051 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Tru by Hilton Beaufort, SC
Outdoor pool
Home2 Suites BY Hilton Beaufort, SC

Home2 Suites BY Hilton Beaufort, SC

Home2 Suites BY Hilton Beaufort, SC
3.0 star property
7.6 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (722)
"Room was spotless and beds comfortable"
United States
Judy
The price is P6,591
P7,250 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Home2 Suites BY Hilton Beaufort, SC
View from property
Cuthbert House

Cuthbert House

Cuthbert House
4.5 star property
6.1 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (951)
"Excellent accommodations. Staff was very friendly & helpful. Will definitely come back. The Inn is beautiful. "
United States
Melanie
The price is P22,121
P24,334 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Cuthbert House
Reception
Hampton Inn Beaufort

Hampton Inn Beaufort

Hampton Inn Beaufort
2.5 star property
6.8 km from Lowcountry Estuarium
8.4 out of 10, Very Good, (1000)
"Room was spotless and staff very courtesy."
United States
Griselda
The price is P5,591
P6,150 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Hampton Inn Beaufort
Exterior
Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort
3.0 star property
7 km from Lowcountry Estuarium
8.4 out of 10, Very Good, (1000)
"Good hotel"
United States
joshua
The price is P5,002
P5,502 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hilton Garden Inn Beaufort
Terrace/patio
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
3.0 star property
7.1 km from Lowcountry Estuarium
8.2 out of 10, Very Good, (1002)
"Beautiful hotel, love the breakfast, wonderful staff"
United States
Jaye
The price is P5,227
P5,750 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
Lobby lounge
Comfort Suites near MCAS Beaufort

Comfort Suites near MCAS Beaufort

Comfort Suites near MCAS Beaufort
2.5 star property
6.5 km from Lowcountry Estuarium
7.4 out of 10, Good, (1001)
"I felt safe and the room was very clean. I received great customer service "
United States
Tonya
The price is P5,243
P6,091 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites near MCAS Beaufort
Exterior
Sleep Inn Beaufort near MCAS

Sleep Inn Beaufort near MCAS

Sleep Inn Beaufort near MCAS
2.5 star property
7 km from Lowcountry Estuarium
7.4 out of 10, Good, (1000)
"Overall i would stay here again."
United States
Joshua
The price is P4,942
P5,437 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Sleep Inn Beaufort near MCAS
Exterior
Country Inn & Suites by Radisson, Beaufort West, SC

Country Inn & Suites by Radisson, Beaufort West, SC

Country Inn & Suites by Radisson, Beaufort West, SC
2.5 star property
6.9 km from Lowcountry Estuarium
7.2 out of 10, Good, (1003)
"I enjoyed everything. Parking, breakfast, staff, and parking was good. "
United States
Deaven
The price is P5,434
P5,977 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Country Inn & Suites by Radisson, Beaufort West, SC
Desk, iron/ironing board, free WiFi, bed sheets
Oasis Inn

Oasis Inn

Oasis Inn
2.5 star property
7 km from Lowcountry Estuarium
7.4 out of 10, Good, (596)
"Fantastic stay. The staff was very friendly and helpful and the rooms were what I needed. Thank you "
United States
Chris
The price is P5,296
P5,825 total
includes taxes & fees
Dec 26 - Dec 27
Oasis Inn
Free daily on-the-go breakfast
Howard Johnson by Wyndham Beaufort/Parris Island

Howard Johnson by Wyndham Beaufort/Parris Island

Howard Johnson by Wyndham Beaufort/Parris Island
2.0 star property
7.7 km from Lowcountry Estuarium
6.0 out of 10, (896)
"Room was good "
United States
INDIRA
The price is P4,631
P5,094 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Howard Johnson by Wyndham Beaufort/Parris Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lowcountry Estuarium Hotel Reviews

Super 8 by Wyndham Port Royal/Beaufort

Super 8 by Wyndham Port Royal/Beaufort

10/10 Excellent
"The room could have been a little cleaner but all and all it was Great! "
Gina 2-night trip
Posted 3 weeks ago
Super 8 by Wyndham Port Royal/Beaufort
Fire Pit + Yard: Charming Port Royal Home!

Fire Pit + Yard: Charming Port Royal Home!

10/10 Excellent
"Loved staying at the Happy Little Cottage! It has all the amenities you could want. The neighborhood is very quoet. Our weather was lots of rain so we didn't get to use the firepit. We would love to stay there again the next time we come to Beaufort."
Virginia 3-night trip
Posted 3 months ago
Fire Pit + Yard: Charming Port Royal Home!

Hotels near other Lowcountry Estuarium attractions

Cypress Wetlands

3.8/5 (10 reviews)
Explore the great outdoors at Cypress Wetlands, a lovely green space in Port Royal. Stroll along the beautiful beaches or visit the shops in this family-friendly area.
See properties

The Sands

4.1/5 (55 reviews)
Why not spend a carefree afternoon at The Sands during your travels in Port Royal? Stroll along this family-friendly area's waterfront, or simply enjoy its restaurants.
See properties

Frequently asked questions

What's the area like around Lowcountry Estuarium?
Lowcountry Estuarium is located in a family-friendly area of Port Royal known for its beautiful island views and major shopping area. If you're looking for a convenient place to stay, check out the 63 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Lowcountry Estuarium?
Located 1.4 mi (2.3 km) from Lowcountry Estuarium, Super 8 by Wyndham Port Royal/Beaufort is one of the top choices for your stay based on our traveler data.
How many hotels are there near Lowcountry Estuarium?
Expedia has 63 hotels and other accommodations within a mile from Lowcountry Estuarium.
If I need to cancel the hotel reservation for my stay near Lowcountry Estuarium, will I receive a refund?
Yes, most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals near Lowcountry Estuarium.
What can I see and do near Lowcountry Estuarium?
You'll want to browse the exhibits at Parris Island Museum and Beaufort Museum. Beaufort National Cemetery, John Mark Verdier House, and St. Helena's Episcopal Church are well-known local landmarks worth a visit. Get outside and spend some time strolling around Henry C. Chambers Waterfront Park, Cypress Wetlands, and Port Royal Skateboard Park.