A sunset over a beach with a pier extending into the water.

Hotels with Spa in Los Osos, California

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Check availability on Los Osos Hotels with Spa

Tonight
Sep 21 - Sep 22
Tomorrow
Sep 22 - Sep 23
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Los Osos hotels with a spa

1. Madonna Inn

Madonna Inn
San Luis Obispo
  • Unwind at a unique spa retreat with six treatment rooms for aromatherapy, body scrubs, and massages in scenic comfort.
Madonna Inn

2. Avila La Fonda Hotel

Avila La Fonda Hotel
Avila Beach
  • Revitalizing seaside escape with private indoor hot tubs and spa services offers a wellness retreat just steps from the beach.
P14,374
P16,171 total
includes taxes & fees
Sep 30 - Oct 1
Avila La Fonda Hotel

3. Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B
Cayucos
  • Relax in a beachside inn with private hot tubs, garden views, and rejuvenating couples massages.
P11,085
P12,471 total
includes taxes & fees
Sep 22 - Sep 23
Cayucos Sunset Inn B&B

4. HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection
Downtown San Luis Obispo
  • Tranquil urban retreat with steam room, rooftop garden, and holistic treatments for a restorative wellness escape.
P16,509
P20,910 total
includes taxes & fees
Sep 28 - Sep 29
HOTEL CERRO, Autograph Collection

5. Hotel San Luis Obispo

Hotel San Luis Obispo
Downtown San Luis Obispo
  • Savor serenity at this luxury hotel with a full-service spa offering daily treatments and couples' massage rooms in San Luis Obispo.
P23,671
P26,866 total
includes taxes & fees
Oct 4 - Oct 5
Hotel San Luis Obispo

6. The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection
Arroyo Grande
  • Revitalize mind and body at this charming hotel with therapeutic spa services and a bubbling hot tub.
P9,625
P10,943 total
includes taxes & fees
Sep 22 - Sep 23
The Agrarian Hotel, BW Signature Collection
View all properties

Choose what matters most at spa hotels in Los Osos

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Los Osos Hotel Reviews

SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

10/10 Excellent
"Great place to stay and relax."
Anesh 2-night trip
Posted 11 hours ago
SeaCrest OceanFront Hotel
Best Western Casa Grande Inn

Best Western Casa Grande Inn

10/10 Excellent
"The rooms were large and well maintained with every amenity necessary. The lady serving the breakfast was kind and very helpful."
Richard 2-night trip
Posted 11 hours ago
Best Western Casa Grande Inn
Oxford Suites Pismo Beach

Oxford Suites Pismo Beach

10/10 Excellent
"This is my second time staying at Oxford suites and the experience just gets better"
martin 2-night trip
Posted 12 hours ago
Oxford Suites Pismo Beach
Spyglass Inn

Spyglass Inn

10/10 Excellent
"Air conditioner worked well great location nice for walking. Great fire pits. Wish you could see the view of the ocean more from the fire pit but still a good spot."
Salisa 1-night trip
Posted 12 hours ago
Spyglass Inn
Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo

10/10 Excellent
"The property is excellent. Well maintained and many different areas to sit outside. Breakfast is exceptional. You get served a full breakfast. The room is awesome....an area to sit and watch tv separate from the bedroom. And pocket door for quiet. Very walkable to downtown"
Jo Ann 3-night trip
Posted 12 hours ago
Quality Suites Downtown San Luis Obispo
Embassy Suites by Hilton San Luis Obispo

Embassy Suites by Hilton San Luis Obispo

10/10 Excellent
"Very nice and clean hotel"
Gabby 1-night trip
Posted 13 hours ago
Embassy Suites by Hilton San Luis Obispo
Madonna Inn

Madonna Inn

8/10 Good
"Julia the hotel the receptionist. Very young person. Help us. Told her. My wife and I are seniors. I Didn't say too much. Anyway don't know this place. She booked us on 3rd floor room #180. My wife has trouble walking. We have our dining reservations for 5:30. All the inconvenience of the staff, the pick up on the golf cart waiting 35 minutes. Anyway we settled down, because we had a wonderful dinner for my 73rd birthday"
francisco 1-night trip
Posted 14 hours ago
Madonna Inn
Edgewater Inn And Suites

Edgewater Inn And Suites

10/10 Excellent
"I go at least twice a year, I never want to stay at another hotel while visiting Pismo! I love how the edgewater is on the beach! Once you park you never need to drive anywhere! You have the beach right there, pool, jacuzzi, shopping, restaurants, market, literally within walking distance! And the staff is always so friendly, accommodating, and I love how they text you so if you need anything the staff is within your fingertips! I have no complaints! I love the edgewater I’ll be back sooner! I’ve been twice this year and I’ll be back in November! But who’s complaining? Not me !! I can’t wait to come back!"
ASHLEE 3-night trip
Posted 14 hours ago
Edgewater Inn And Suites
Inn at the Cove

Inn at the Cove

10/10 Excellent
"Spend the extra $$ to get a room on 2nd floor with Pool & bay view! Beautiful! Also, close to Alex Madonna's Steakhouse! We will return!"
Herschal 1-night trip
Posted 16 hours ago
Inn at the Cove

Frequently asked questions

Looking for a spa hotel in Los Osos?
Forget the stress of everyday life and book yourself a hotel with a spa. Check out the beaches in Los Osos - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Los Osos?
Sea Pines Resort is a top spa hotel featuring a golf course, a bar, and a restaurant. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages, and couples treatments.
How many spa hotels will I find in Los Osos?
Among Expedia's 44 accommodation options in Los Osos, there is 1 spa hotel.
What's there to see and do in Los Osos?
Experience Los Osos with a stop at Morro Coast Audubon Society Sweet Springs Nature Preserve, Montaña de Oro State Park, and Morro Bay State Park. If you have a bit of extra time while you're in the area, you might want to check out Los Osos Oaks State Reserve and Islay Creek Trail.
What is a Los Osos spa hotel?
Spa hotels in Los Osos provide lodging and have an on-site spa which offers services such as facials as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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