Los Anastacios Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Apr 17 - Apr 19
In two months
May 29 - May 31
In three months
Jun 26 - Jun 28
In four months
Jul 24 - Jul 26

Our top choices for Los Anastacios vacation rentals

View from room

Lucero - Luxury Treehouses

Lucero - Luxury Treehouses
3.5 star property
Jaramillo
8.8 out of 10, Excellent, (5 reviews)
"Print or save your map beforehand. Do not exit onto a gravel road! The property is located inside a golf community. The map on the listing is incorrect! As of October 2025 all maps including Google, Waze and Apple maps all have the wrong and remote location. The correct location is Lucero. We had a beautiful experience! Everyone was so pleasant and welcoming. We had an amazing stay!"
United States
John
The price is P14,244
P15,668 total
includes taxes & fees
Apr 6 - Apr 7
Lucero - Luxury Treehouses
Front of property

Aires frescos de Boquete

Aires frescos de Boquete
3.0 star property
Alto Boquete
9.0 out of 10, Wonderful, (4 reviews)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
The price is P3,104
P3,415 total
includes taxes & fees
Apr 11 - Apr 12
Aires frescos de Boquete
Exterior

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (17 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
The price is P2,976
P3,273 total
includes taxes & fees
May 4 - May 5
Linda Vista Cabins
Living area

Peace N' Green

Peace N' Green
3.0 star property
David
The price is P5,421
P5,963 total
includes taxes & fees
Apr 10 - Apr 11
Peace N' Green
Premium bedding, down comforters, individually decorated

Casa Mate by Villa Alejandro

Casa Mate by Villa Alejandro
3.5 star property
Los Naranjos
6.0 out of 10, (2 reviews)
The price is P3,762
P5,289 total
includes taxes & fees
Apr 30 - May 1
Casa Mate by Villa Alejandro
Living area

Villa Alejandro

Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (143 reviews)
"We enjoyed the clean common areas, coffee, water and friendly staff. The room was small but adequate. Bathroom was very small and clean"
Canada
norma
The price is P3,108
P4,685 total
includes taxes & fees
Apr 28 - Apr 29
Villa Alejandro
2 bedrooms, iron/ironing board, free WiFi

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo

Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
3.0 star property
El Tropezón
The price is P6,978
P13,633 total
includes taxes & fees
Apr 15 - Apr 16
Parkside Plazuela - Tranquility In Boquete 2 Bedroom Condo
Private spa tub

Casa Reina by Villa Alejandro

Casa Reina by Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (19 reviews)
"Be aware the road, or trail more like it, to the hotel is very rough, only 1 lane in same areas. Check in took 15 minutes, with remote concierge. Views from balcony is great. Grounds are well kept. lots of small birds singing. Room is large and king bed is comfortable."
United States
Tim
The price is P4,362
P5,949 total
includes taxes & fees
Apr 28 - Apr 29
Casa Reina by Villa Alejandro
1 bedroom, Egyptian cotton sheets, pillowtop beds, free WiFi

Downtown Suites

Downtown Suites
3.0 star property
El Tropezón
9.0 out of 10, Wonderful, (105 reviews)
"Construction noise, but they stopped working at 6pm so didn't affect us much as we stayed for 1 night "
Canada
Alexandr
The price is P3,971
P4,368 total
includes taxes & fees
May 3 - May 4
Downtown Suites
Garden

Aparthotel Los Pinos

Aparthotel Los Pinos
2.5 star property
Boquete
8.6 out of 10, Excellent, (17 reviews)
"The place was spacious, clean and comfortable. Great location and easy parking."
United States
Rebecca
The price is P6,014
P6,615 total
includes taxes & fees
May 4 - May 5
Aparthotel Los Pinos
Premium bedding, down comforters, individually decorated

El Cielo by Villa Alejandro

El Cielo by Villa Alejandro
3.5 star property
Boquete
9.4 out of 10, Exceptional, (105 reviews)
"Everything was perfect! The room was comfortable and clean. The proximity to town was great!Communication with the hosts was excellent!"
United States
Lee
The price is P4,164
P5,846 total
includes taxes & fees
May 3 - May 4
El Cielo by Villa Alejandro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Los Anastacios Hotel Reviews

Valle Escondido Resort

Valle Escondido Resort

6/10 Okay
"There is no service and no one answers the phone and they can’t fix even transportation. Area is beautiful but the hotel is not up to standards. "
Mario 1-night trip
Posted 2 days ago
Valle Escondido Resort

Find out more about Los Anastacios

Search for holiday rentals in Los Anastacios on Expedia! You can easily find your home rentals, villas, holiday apartments in Los Anastacios using one of the methods below:

  • View our selection of featured holiday rentals in Los Anastacios
  • Use the map to find apartments and other holiday homes in the Los Anastacios neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Los Anastacios while they last

Look no further and take a look at our great range of rental properties in Los Anastacios!

Frequently asked questions

Can I find a vacation rental in Los Anastacios?

Yes, we offer vacation rentals close to popular points of interest in Los Anastacios, or you can go with a more remote option if you're looking for relaxation.

What are some of the best vacation rentals in Los Anastacios?

Aires frescos de Boquete: You might want to consider this vacation rental near Los Anastacios, which is equipped with a garden, free WiFi, and a Smart TV to help you feel comfortable during your stay. Kitchen amenities like a full-sized fridge and a microwave can make your vacation run smoothly.

What’s there to see and do in Los Anastacios?

While you're exploring the area, Parque de las Madres and Miguel de Cervantes Saavedra Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Boquete Library and Municipal Park.

What are vacation rentals like in Los Anastacios?

Vacation rentals are privately owned properties you can book for a few days or a quick weekend in Los Anastacios. Vacation rentals feature amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, vacation rentals can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family gatherings.