Top 10 Hotels Near Lake Issaqueena in Central for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Lake Issaqueena hotels

An outdoor patio area with a fire pit, seating, and string lights.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

1. Tru by Hilton Seneca Clemson

5.8 km from Lake Issaqueena

Melissa

P6,940

P7,634 total

includes taxes & fees

Nov 8 - Nov 9

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A brick building with a sign reading "The Inn at Patrick Square".

A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.

A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".

2. The Inn at Patrick Square

9.2 km from Lake Issaqueena

Jennifer

P9,370

P10,401 total

includes taxes & fees

Oct 26 - Oct 27

A modern kitchen area with a bar counter and seating.

A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.

A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

A modern bar area with high stools and a poolside view.

3. Hampton Inn Clemson-University Area

5.5 km from Lake Issaqueena

Blaise

P6,895

P7,654 total

includes taxes & fees

Oct 26 - Oct 27

A white, two-story house with a front porch, surrounded by trees and shrubs.

A two-story building with a white exterior, a front door, and a balcony.

A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.

A dining area with round tables, black chairs, and white tablecloths.

4. Liberty Hall Bed and Breakfast

13 km from Lake Issaqueena

Christine

P5,755

P6,389 total

includes taxes & fees

Nov 3 - Nov 4

A golf course with a water body, trees, and a distant view of a bridge.

An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

A modern building with a central entrance, surrounded by a well-maintained lawn and trees.

5. Clemson University's James F. Martin Inn

8.7 km from Lake Issaqueena

Lilllian

P9,370

P10,401 total

includes taxes & fees

Oct 19 - Oct 20

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A modern lobby with a reception desk, seating area, and a vending machine.

6. Fairfield Inn & Suites Seneca Clemson Univ Area

10.6 km from Lake Issaqueena

Lori

P7,564

P8,321 total

includes taxes & fees

Nov 1 - Nov 2

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

7. Lakeside Lodge Clemson

5.6 km from Lake Issaqueena

Lori

P6,854

P8,509 total

includes taxes & fees

Oct 19 - Oct 20

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.

A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

8. The Shepherd Hotel Downtown Clemson

6.7 km from Lake Issaqueena

Laurrie

P13,143

P14,589 total

includes taxes & fees

Oct 26 - Oct 27

A modern bar area with a menu board, bar stools, and a countertop with various items.

A Courtyard Marriott hotel with a brick facade, multiple floors, and a covered entrance area.

An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

A modern dining area with a bar, bar stools, and a patterned rug.

9. Courtyard Marriott Clemson

7.3 km from Lake Issaqueena

kim

P6,993

P7,762 total

includes taxes & fees

Nov 1 - Nov 2

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.

A conference room with a large round table, multiple chairs, and a projector.

A hotel room with a large bed, bedside tables, a desk with a chair, a TV, and a window with a view.

10. Holiday Inn Express & Suites Clemson by IHG

7.1 km from Lake Issaqueena

P8,112

P9,005 total

includes taxes & fees

Oct 25 - Oct 26

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

A bar area with a counter, multiple chairs, and a display of bottles and glasses.

11. The Abernathy of Clemson

6.7 km from Lake Issaqueena

Amy

P10,697

P11,873 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.

A hotel reception area with two reception desks, a digital screen, and a tiled floor.

A spacious room with a large window, a flat-screen TV mounted on the wall, and a seating area with sofas and chairs.

12. Comfort Inn & Suites Clemson - University Area

6.6 km from Lake Issaqueena

Beverly

P6,646

P7,377 total

includes taxes & fees

Nov 15 - Nov 16

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

A reception area with a counter, chairs, and a patterned rug.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

13. Hampton Inn & Suites Seneca-Clemson Area

8.6 km from Lake Issaqueena

Lloyd

P7,774

P8,551 total

includes taxes & fees

Oct 25 - Oct 26

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

A hotel room with two beds, a desk, a television, and a clock on the wall.

A wall with a decorative design featuring a building, trees, and a sky with clouds.

14. Inn @ Clemson

6.5 km from Lake Issaqueena

Kristi

P5,037

P5,591 total

includes taxes & fees

Oct 27 - Oct 28

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

15. Quality Inn Seneca US-123

13.5 km from Lake Issaqueena

Barry

P5,263

P6,183 total

includes taxes & fees

Oct 19 - Oct 20

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

A wooden interior with a table, chair, and a hanging lantern.

A cabin in a forest with a small deck and outdoor seating area.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

16. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

15.8 km from Lake Issaqueena

Winston

P5,864

P9,225 total

includes taxes & fees

Nov 16 - Nov 17

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A lobby with seating areas, a reception desk, and a patterned wall.

A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

17. Best Western Plus Clemson Hotel & Conference Center

6.8 km from Lake Issaqueena

David

P6,646

P7,377 total

includes taxes & fees

Nov 16 - Nov 17

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

18. Best Western Seneca-Clemson

9.7 km from Lake Issaqueena

Michelle

P6,378

P7,016 total

includes taxes & fees

Nov 16 - Nov 17

A kitchen with a coffee maker, microwave, and refrigerator.

A hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted lamp.

A reception area with a check-in desk, a seating area with a bench, and a wall-mounted display of postcards.

A hotel room with a bed, a desk with a chair, a television, a small table, and a microwave.

19. Rodeway Inn & Suites Walhalla

17.7 km from Lake Issaqueena

Richard

P4,555

P5,079 total

includes taxes & fees

Nov 15 - Nov 16

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.

A gazebo with a tiled roof and a surrounding gravel area.

20. Days Inn by Wyndham Clemson

7.1 km from Lake Issaqueena

David

P5,051

P5,606 total

includes taxes & fees

Oct 18 - Oct 19

View all properties

Compare popular hotels close to Lake Issaqueena

Property	Property class	Guest rating
Tru by Hilton Seneca Clemson	9.2 Wonderful 900 reviews	View
The Inn at Patrick Square	9.8 Exceptional 927 reviews	View
Hampton Inn Clemson-University Area	8.8 Excellent 651 reviews	View
Liberty Hall Bed and Breakfast	9.8 Exceptional 104 reviews	View
Clemson University's James F. Martin Inn	9.4 Exceptional 1,006 reviews	View

Top Lake Issaqueena Hotel Reviews

The Abernathy of Clemson

8/10 Good

"The hotel staff was very nice. The room and property were clean. Right across the street from campus and close to lots of food options. Parking was included. They do not have an onsite gym and did not have a store with necessities such as medicine."

Tru by Hilton Seneca Clemson

10/10 Excellent

"The staff were very friendly and everything was nice and clean! A great selection for breakfast!"

Inn @ Clemson

10/10 Excellent

"Clean room, comfortable beds, good breakfast, great price!"

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"We will stay here again if we go to Clemson. Room was excellent...staff was excellent and the breakfast room and food was excellent!"

Other attractions near Lake Issaqueena

Larry W. Abernathy Waterfront Park

8.6/10 (58 reviews)

Larry W. Abernathy Waterfront Park is just one of the places to see in Clemson, so why not enjoy the other things to explore during your travels? Experience the area's theater scene or attend a football game.

See properties

Littlejohn Coliseum

9.4/10 (141 reviews)

Catch an event at Littlejohn Coliseum during your trip to Clemson. Amble around the area's lakeside or attend a football game.

See properties

Sloan Tennis Center

Catch an event at Sloan Tennis Center during your trip to Clemson. You can attend a football game while in the area.

See properties

Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

See properties

Clemson Area African American Museum

You can spend time browsing the exhibits at Clemson Area African American Museum in Clemson. You can attend a football game while in the area.

See properties

Wyndham Plaza

You can browse for the perfect souvenirs at Wyndham Plaza during your visit to Seneca. Stroll along the lakeside or attend a sporting event in this family-friendly area.

See properties

World of Energy

You can spend an afternoon exploring the galleries in World of Energy in Seneca. Amble around this family-friendly area's lakeside or attend a sporting event.

See properties

Frequently asked questions

What's the area like around Lake Issaqueena?

Lake Issaqueena is located in Central. You'll find 209 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay near Lake Issaqueena?

Lakeside Lodge Clemson is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 3.5 mi (5.6 km) from Lake Issaqueena. Other good choices within a few miles include Best Western Plus Clemson Hotel & Conference Center and Comfort Inn & Suites Clemson - University Area.

How many hotels are there close to Lake Issaqueena?

Expedia has 209 hotels and other accommodations a few miles from Lake Issaqueena.

If I need to cancel the hotel reservation for my stay near Lake Issaqueena, will I receive a refund?

Yes! Most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to review the top deals on offer near Lake Issaqueena.

What can I see and do near Lake Issaqueena?

You'll want to browse the exhibits at Fort Hill and Clemson Area African American Museum. Explore nature at Keowee Reservoir and Larry W. Abernathy Waterfront Park. If you've got some time to explore the area around Lake Issaqueena, you may want to make a stop by Littlejohn Coliseum, Memorial Stadium, and Sloan Tennis Center.

Hotels near Lake Issaqueena

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lake Issaqueena hotels

1. Tru by Hilton Seneca Clemson

2. The Inn at Patrick Square

3. Hampton Inn Clemson-University Area

4. Liberty Hall Bed and Breakfast

5. Clemson University's James F. Martin Inn

6. Fairfield Inn & Suites Seneca Clemson Univ Area

7. Lakeside Lodge Clemson

8. The Shepherd Hotel Downtown Clemson

9. Courtyard Marriott Clemson

10. Holiday Inn Express & Suites Clemson by IHG

11. The Abernathy of Clemson

12. Comfort Inn & Suites Clemson - University Area

13. Hampton Inn & Suites Seneca-Clemson Area

14. Inn @ Clemson

15. Quality Inn Seneca US-123

16. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

17. Best Western Plus Clemson Hotel & Conference Center

18. Best Western Seneca-Clemson

19. Rodeway Inn & Suites Walhalla

20. Days Inn by Wyndham Clemson

Compare popular hotels close to Lake Issaqueena

Top Lake Issaqueena Hotel Reviews

The Abernathy of Clemson

Tru by Hilton Seneca Clemson

Inn @ Clemson

Comfort Inn & Suites Clemson - University Area

Other attractions near Lake Issaqueena

Larry W. Abernathy Waterfront Park

Littlejohn Coliseum

Sloan Tennis Center

Memorial Stadium

Clemson Area African American Museum

Wyndham Plaza

World of Energy

Frequently asked questions