A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Hotels with Spa in Key Largo, Florida

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Check availability on Key Largo Hotels with Spa

Our top choices for Key Largo hotels with a spa

A hotel room with a bed, a dresser, a mirror, and a nightstand.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,572 reviews)
  • cleanliness
    Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
The price is P13,956
P18,250 total
includes taxes & fees
Nov 29 - Nov 30
Reefhouse Resort & Marina
A spacious interior with a high ceiling, large windows, and a central light fixture.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.8 out of 10, Excellent, (1,199 reviews)
The price is P16,773
P22,382 total
includes taxes & fees
Nov 29 - Nov 30
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A spacious lobby with hanging chairs, a round wooden table with a starfish and a cactus, and a reception desk in the background.

3. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1,004 reviews)
  • cleanliness
    Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
The price is P16,760
P22,368 total
includes taxes & fees
Nov 29 - Nov 30
Playa Largo Resort & Spa, Autograph Collection
A beach with palm trees, a thatched-roof structure, and kayaks.

4. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (368 reviews)
  • cleanliness
    Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
The price is P9,693
P12,697 total
includes taxes & fees
Nov 16 - Nov 17
Kona Kai Resort and Gallery - Adults Only
A wooden table with two white cups, one with coffee and one with tea, placed on a body of water.

5. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
3.5 star property
Key Largo
9.6 out of 10, Exceptional, (4 reviews)
  • cleanliness
    Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
The price is P52,435
P58,990 total
includes taxes & fees
Nov 16 - Nov 17
Premium Floating Bungalow by Stay Ombi
A conference room with a large painting of a blue ocean, two Laptops, and wicker chairs.

6. Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,518 reviews)
  • cleanliness
    Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
The price is P11,554
P17,658 total
includes taxes & fees
Nov 16 - Nov 17
Cheeca Lodge & Spa
A hotel room with two beds, a large window with a view of a balcony, and a curtain on the window.

7. The Islands of Islamorada

The Islands of Islamorada
5.0 star property
Matecumbe
9.6 out of 10, Exceptional, (83 reviews)
  • cleanliness
    Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
The price is P44,736
P54,988 total
includes taxes & fees
Nov 30 - Dec 1
The Islands of Islamorada
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Key Largo

Pool
Hot tub

Top Key Largo Hotel Reviews

Dove Creek Resort & Marina, Trademark Collection by Wyndham

Dove Creek Resort & Marina, Trademark Collection by Wyndham

8/10 Good
"Highly recommended !...My wife and I spent an anniversary weekend there and it was really enjoyable...the view is fabulous, the amenities were just what we needed. The entire place is nicely kept...beautiful room with a balcony !"
FEDERICO 2-night trip
Posted 7 hours ago
Dove Creek Resort & Marina, Trademark Collection by Wyndham

Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a top beach spa hotel featuring 4 restaurants, 3 bars, a 24-hour fitness center, and a hair salon. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Another popular spa hotel in Key Largo is Reefhouse Resort & Marina.
How many spa hotels will I find in Key Largo?
Among Expedia's 1296 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a bit of extra time while you're in the area, you might want to check out John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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