Top 10 Hotels Near James S. McDonnell Prologue Room in St. Louis for 2026

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Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A hotel room with a bed, a desk, a television, and a lamp.

1. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Murphy

P5,648

P6,706 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

2. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Mary

P6,075

P7,213 total

includes taxes & fees

Oct 22 - Oct 23

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A pool area with two hot tubs, seating, and a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

3. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Ethan

P7,217

P8,540 total

includes taxes & fees

Oct 18 - Oct 19

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern lobby with blue seating, a reception desk, and large windows.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

4. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Daisy

P6,903

P8,559 total

includes taxes & fees

Oct 26 - Oct 27

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A snack vending machine with various snack options.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Leia

P8,083

P9,727 total

includes taxes & fees

Oct 29 - Oct 30

A breakfast buffet with labeled sections for fruit and cereal.

A kitchen area with wooden cabinets, a refrigerator, and shelves stocked with various food items.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A Holiday Inn Express & Suites building with a covered entrance, a truck with the hotel branding, and a clear sky.

6. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

P7,468

P9,238 total

includes taxes & fees

Nov 13 - Nov 14

A buffet with fruits, pastries, and beverages.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

7. Renaissance St. Louis Airport Hotel

2 km from James S. McDonnell Prologue Room

Anthony

P7,415

P8,675 total

includes taxes & fees

Oct 29 - Oct 30

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

A modern lobby with seating areas, a reception desk, and a bar area.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Sha

P8,955

P10,776 total

includes taxes & fees

Oct 30 - Oct 31

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

A modern kitchen with a marble countertop, red ceiling, and pendant lighting.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Samone

P6,672

P7,896 total

includes taxes & fees

Nov 1 - Nov 2

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A modern hotel lobby with a large seating area, a bar, and a reception desk.

A multi-story hotel with a prominent 'Hilton' sign, a parking area, and a covered walkway.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

raymond

P8,608

P10,359 total

includes taxes & fees

Nov 13 - Nov 14

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel room with a round wooden dining table, a sofa, two lamps, and framed pictures on the walls.

A workspace with two desks, two computers, a clock, and a framed picture on the wall.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Annalyn

P4,124

P4,913 total

includes taxes & fees

Nov 8 - Nov 9

A reception desk with a cityscape on the monitor, a blue-lit ceiling, and a sign for key drop-off.

A modern hotel with a covered entrance, large windows, and a sign indicating a one-way street.

A restaurant with tables and chairs, a coffee machine, and a refrigerator.

Two white front-loading washers stacked on top of each other with a Gain detergent box and a Whirlpool instruction manual on the top washer.

12. Travelodge by Wyndham St. Louis

2.4 km from James S. McDonnell Prologue Room

Monica

P3,828

P4,532 total

includes taxes & fees

Nov 1 - Nov 2

A parking lot with multiple cars, a building with a green and beige facade, and a sign for Home Towne Studios.

A compact kitchenette with a sink, stove, microwave, and a white refrigerator.

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

13. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

P3,840

P4,694 total

includes taxes & fees

Oct 19 - Oct 20

A hotel room with a large bed, bedside tables, a heater, and a view of the city.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

A modern living room with a grey sofa, a red bench, a dark wooden table, and a TV on a stand.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

14. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

Fed

P4,707

P5,754 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

15. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

P3,502

P4,354 total

includes taxes & fees

Nov 1 - Nov 2

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A gym with treadmills, stationary bikes, and a weight machine.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

16. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Robert

P9,099

P10,549 total

includes taxes & fees

Oct 18 - Oct 19

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

A spa bath with a sign indicating a capacity of 8 persons.

17. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Janell

P8,033

P9,540 total

includes taxes & fees

Nov 1 - Nov 2

A courtyard with outdoor seating, a central fountain, and a view of a tower.

A buffet setup with various food items, a coffee station, and a refrigerator with beverages.

A hotel room with two beds, a desk, and a chair.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

18. The Knight Center at Washington University

11.4 km from James S. McDonnell Prologue Room

Rosalyn

P9,561

P10,993 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A snack and treat display with various products, including chips and beverages, in a store setting.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

19. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Melissa

P8,703

P10,263 total

includes taxes & fees

Nov 9 - Nov 10

A brick building with a sign reading "Country Inn & Suites."

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

20. Country Inn & Suites by Radisson, St. Charles Historic District

12.5 km from James S. McDonnell Prologue Room

Roseanna

P8,195

P9,419 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,290 reviews	View
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,696 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,440 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,006 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 241 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

8/10 Good

"The property was great but the breakfast menu was the same every morning. I would’ve liked a little more variety. The happy hour cocktails were nice. The room and property were clean. I would’ve liked highly recommend thus property."

Hyatt Select St. Louis Airport

10/10 Excellent

"Cedes was wonderful. So pleasant and very friendly. I definitely would return because of her."

Travelodge by Wyndham St. Louis

10/10 Excellent

"My second year staying here and it’s a great place for me based on the location (close to the airport), amenities (breakfast and laundry), transit (buses, Red line, and Enterprise and Uber extremely close by), and food choices nearby. The staff are really friendly and helpful, and the price of my room is very affordable and cheaper than most places in the area. I’ve never had a vehicle staying here but the free parking is always available with plenty of space when I’m here (August and October). My room was always quiet (107 and 115)."

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"Everything!! I vote a 10/10. The front desk staff, manager, housekeeping, breakfast, hospitality were top notch!!! Myself and my family totally enjoyed our stay and will stay again!! I thank GOD we stayed somewhere that we also felt safe due to only ones that stayed could get being the gate."

Quality Inn Saint Louis Airport

8/10 Good

"Our stay was short and accommodating"

Quality Inn Florissant - St Louis

8/10 Good

"It was 4.0 stay. Could have been cleaner but was adequate, affordable, and beds were comfy for the price. Kind of get what you pay for."

Marriott St. Louis Airport

10/10 Excellent

"n/a"

Comfort Inn & Suites Hazelwood - St. Louis

10/10 Excellent

"Best time ever"

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you spend time at Payne-Gentry Historical House. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine in Florissant. Experience the great live music and acclaimed theater scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time exploring the galleries in St. Louis Car Museum during your travels in Overland. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time studying the exhibits at St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theater scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your trip to St. Louis. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodations a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best options available near James S. McDonnell Prologue Room.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're checking out the area.

Hotels near James S. McDonnell Prologue Room

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Wingate by Wyndham St. Louis Airport

3. Drury Inn & Suites St. Louis Airport

4. Hyatt Select St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Holiday Inn Express & Suites St Louis Airport by IHG

7. Renaissance St. Louis Airport Hotel

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. Travelodge by Wyndham St. Louis

13. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

14. Welcome Suites Hazelwood

15. Quality Inn Saint Louis Airport

16. Drury Plaza Hotel St. Louis St. Charles

17. Drury Plaza Hotel St. Louis Brentwood

18. The Knight Center at Washington University

19. Hampton Inn & Suites St. Louis at Forest Park

20. Country Inn & Suites by Radisson, St. Charles Historic District

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

Hyatt Select St. Louis Airport

Travelodge by Wyndham St. Louis

Drury Inn & Suites St. Louis Airport

Quality Inn Saint Louis Airport

Quality Inn Florissant - St Louis

Marriott St. Louis Airport

Comfort Inn & Suites Hazelwood - St. Louis

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions