Hotels near Historic Main Street

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Our top choices for Historic Main Street hotels

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District, 1 km from Historic Main Street
9.4 out of 10, Exceptional, (1005)
"Everything was great!"
United States
Rita
The price is P6,828
P7,847 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Country Inn & Suites by Radisson, St. Charles Historic District

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
1.8 km from Historic Main Street
9.6 out of 10, Exceptional, (1008)
"Staff and hotel were amazing"
United States
Allison
The price is P6,752
P7,828 total
includes taxes & fees
Dec 28 - Dec 29
Drury Plaza Hotel St. Louis St. Charles

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
1.5 km from Historic Main Street
9.2 out of 10, Wonderful, (636)
"Huge room. Great breakfast. "
United States
David
The price is P6,517
P7,848 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn & Suites St. Charles Old Town Area

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
2.1 km from Historic Main Street
8.8 out of 10, Excellent, (1016)
"Breakfast was excellent along with clean comfortable beds. "
United States
Scott
The price is P7,175
P8,246 total
includes taxes & fees
Dec 29 - Dec 30
Embassy Suites by Hilton St. Louis St. Charles

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
1.4 km from Historic Main Street
8.4 out of 10, Very Good, (1010)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is P8,935
P11,416 total
includes taxes & fees
Dec 24 - Dec 25
Ameristar Casino Resort and Spa

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
1.5 km from Historic Main Street
8.4 out of 10, Very Good, (1000)
"Nice staff at reception. "
United States
Denise
The price is P4,633
P5,324 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Suites St Charles - St Louis

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
2.1 km from Historic Main Street
8.6 out of 10, Excellent, (772)
"Great hotel! "
United States
Royally
The price is P5,889
P6,827 total
includes taxes & fees
Dec 28 - Dec 29
Tru by Hilton St. Charles St. Louis, MO

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
1.4 km from Historic Main Street
8.0 out of 10, Very Good, (1005)
"The room is decent for a night. The price is great and hotel staff is friendly. "
United States
Jordan
The price is P5,191
P6,018 total
includes taxes & fees
Dec 28 - Dec 29
Best Western Plus The Charles Hotel

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
3 km from Historic Main Street
8.4 out of 10, Very Good, (2220)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is P6,870
P8,869 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hollywood Casino & Hotel St. Louis

Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
3.5 star property
2.9 km from Historic Main Street
7.6 out of 10, Good, (1001)
"It’s near to the exit to the highway "
United States
Gabriel
The price is P4,345
P4,997 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn St. Louis Arpt West-Earth City by IHG

Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham
3.0 star property
3.1 km from Historic Main Street
7.4 out of 10, Good, (1002)
"Everything was nice"
United States
Ronald
The price is P5,285
P6,130 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Elimwood Hotel, a Ramada by Wyndham

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
1.6 km from Historic Main Street
5.8 out of 10, (1004)
"Nice staff, respectful."
United States
LaurenRenee
The price is P4,110
P4,765 total
includes taxes & fees
Dec 24 - Dec 25
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Sonesta Simply Suites St Louis Earth City

Sonesta Simply Suites St Louis Earth City
2.0 star property
3.3 km from Historic Main Street
8.6 out of 10, Excellent, (805)
"Always a great stay"
United States
Darnell
The price is P4,698
P5,402 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Sonesta Simply Suites St Louis Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City
3.0 star property
4.2 km from Historic Main Street
8.8 out of 10, Excellent, (1002)
"Location wasn’t the greatest but the room was awesome. "
United States
Shawn
The price is P6,107
P7,275 total
includes taxes & fees
Jan 1 - Jan 2, 2026
SpringHill Suites by Marriott St. Louis Airport/Earth City

Courtyard St. Louis Airport/Earth City

Courtyard St. Louis Airport/Earth City
3.0 star property
4.2 km from Historic Main Street
8.4 out of 10, Very Good, (1000)
"Clean, quiet hotel with all the amenities you’d need. Located in a business park which I appreciated as a solo traveler staying overnight in St. Louis on a Saturday night. "
United States
Alissa
The price is P5,931
P7,070 total
includes taxes & fees
Dec 28 - Dec 29
Courtyard St. Louis Airport/Earth City

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
3.6 km from Historic Main Street
7.4 out of 10, Good, (1010)
"Spacious suite, friendly staff. Check in was easy and everything looked clean"
United States
Jonathan
The price is P4,186
P4,855 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
4.7 km from Historic Main Street
8.0 out of 10, Very Good, (1000)
"I'd stay at this place again. "
United States
Suzanne
The price is P4,442
P5,105 total
includes taxes & fees
Dec 29 - Dec 30
Super 8 by Wyndham St Charles

Holiday Inn Express Hotel and Suites St. Charles by IHG

Holiday Inn Express Hotel and Suites St. Charles by IHG
3.0 star property
5 km from Historic Main Street
8.2 out of 10, Very Good, (718)
"Good place to stay"
United States
Dustin
The price is P6,988
P8,031 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Holiday Inn Express Hotel and Suites St. Charles by IHG

Candlewood Suites St Louis St Charles by IHG

Candlewood Suites St Louis St Charles by IHG
2.5 star property
4 km from Historic Main Street
7.6 out of 10, Good, (755)
"Great place to stop to! "
United States
Neil
The price is P4,698
P5,399 total
includes taxes & fees
Dec 29 - Dec 30
Candlewood Suites St Louis St Charles by IHG

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
10.6 km from Historic Main Street
9.4 out of 10, Exceptional, (2760)
"Great place to stay before your early morning flight. "
United States
Henry
The price is P5,284
P6,221 total
includes taxes & fees
Dec 27 - Dec 28
Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Historic Main Street Hotel Reviews

Hotels near other Historic Main Street attractions

Frequently asked questions

What's the area like around Historic Main Street?
Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 90 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Historic Main Street?
Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Other good options close by include Best Western Plus The Charles Hotel and Country Inn & Suites by Radisson, St. Charles Historic District.
How many hotels are there near Historic Main Street?
Expedia has 90 hotels and other accommodations within a mile from Historic Main Street.
If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.
What can I see and do near Historic Main Street?
Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.