Hotels near Hannibal Regional Hospital

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Dec 23 - Dec 24
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Dec 26 - Dec 28
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Our top choices for Hannibal Regional Hospital hotels

Exterior
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
1.3 km from Hannibal Regional Hospital
9.6 out of 10, Exceptional, (1003)
"Great area"
United States
kelvin
The price is P5,700
P6,604 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Sleep Inn & Suites Hannibal West
Lobby
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
1.5 km from Hannibal Regional Hospital
8.0 out of 10, Very Good, (1003)
"Very nice place to stay during a snow storm. "
United States
Teresa
The price is P4,072
P4,718 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn & Suites Hannibal West
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River

Best Western On The River

Best Western On The River
2.5 star property
7.8 km from Hannibal Regional Hospital
8.6 out of 10, Excellent, (1004)
"Great stay! Clean and cozy!!"
United States
Courtney
The price is P5,989
P6,878 total
includes taxes & fees
Dec 24 - Dec 25
Best Western On The River
In-room safe, desk, blackout drapes, iron/ironing board
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
5 km from Hannibal Regional Hospital
7.6 out of 10, Good, (660)
"Below average facility. Needs some upgrades and could use a good cleaning. Staff was helpful."
United States
JACQUI
The price is P4,463
P5,302 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn & Suites - Hannibal
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
8.1 km from Hannibal Regional Hospital
9.4 out of 10, Exceptional, (165)
"Great place to stay!"
United States
Sandy
The price is P8,905
P12,251 total
includes taxes & fees
Dec 27 - Dec 28
Riverside Inn Hannibal
Lobby lounge
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
5.6 km from Hannibal Regional Hospital
7.4 out of 10, Good, (1000)
"Very clean rooms and staff is very friendly "
United States
Sherrie
The price is P3,405
P3,911 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Motel 6 Hannibal, MO
Desk, laptop workspace, free WiFi, bed sheets
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
4.8 km from Hannibal Regional Hospital
7.4 out of 10, Good, (216)
"Left before breakfast great cup of coffee"
United States
David
The price is P3,905
P4,485 total
includes taxes & fees
Dec 24 - Dec 25
Days Inn by Wyndham Hannibal
Exterior
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
5.4 km from Hannibal Regional Hospital
7.2 out of 10, Good, (1000)
"My stay was excellent staff very friendly and breakfast was always great "
United States
Sherrie
The price is P3,435
P3,945 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Super 8 by Wyndham Hannibal
Indoor pool
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
4.9 km from Hannibal Regional Hospital
7.2 out of 10, Good, (152)
"The gentleman at the front desk was extremely nice and did everything to make my stay wonderful. The breakfast was awesome. The pool was sooo nice. The exercise room was great. I cannot say anything bad about this hotel. This was the first time I stayed here and I will be coming back every three months.!"
United States
Shawn
The price is P3,347
P3,871 total
includes taxes & fees
Dec 24 - Dec 25
Howard Johnson BY Wyndham Hannibal
Down comforters, blackout drapes, iron/ironing board, free WiFi
Lighthouse Inn & Suites

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
7.4 km from Hannibal Regional Hospital
8.8 out of 10, Excellent, (24)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is P9,916
P11,388 total
includes taxes & fees
Dec 24 - Dec 25
Lighthouse Inn & Suites
Indoor pool
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
4.9 km from Hannibal Regional Hospital
6.4 out of 10, (737)
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is P3,435
P3,972 total
includes taxes & fees
Dec 25 - Dec 26
Baymont by Wyndham Hannibal
TV
Garden House Bed and Breakfast

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
7.7 km from Hannibal Regional Hospital
8.6 out of 10, Excellent, (38)
"Overall stay was great and the host chris is great aswell nothing bad to say about any aspect of our stay!"
United States
Josh
The price is P6,289
P7,223 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Garden House Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Hannibal Regional Hospital Hotel Reviews

Best Western On The River

Best Western On The River

10/10 Excellent
"Clean and comfortable"
DeLaine 1-night trip
Posted 4 days ago
Best Western On The River

Hotels near other Hannibal Regional Hospital attractions

Hospital Park

Hospital Park is just one of the places to see in Hannibal, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Bear Creek Park

After visiting Bear Creek Park, make a plan to see the other sights and activities in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Hannibal Regional Hospital?
Hannibal Regional Hospital is located in Hannibal. This historic area is known for its array of dining options. You'll find 42 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Hannibal Regional Hospital?
Quality Inn & Suites Hannibal West is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.5 km) from Hannibal Regional Hospital. Other good choices within a short distance include Sleep Inn & Suites Hannibal West and Holiday Inn Express & Suites Hannibal - Medical Center by IHG.
How many hotels will I be able to find close to Hannibal Regional Hospital?
Expedia has 42 hotels and other accommodations a few miles from Hannibal Regional Hospital.
If I need to cancel the hotel reservation for my stay near Hannibal Regional Hospital, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review the best options available near Hannibal Regional Hospital.
What can I see and do near Hannibal Regional Hospital?
Study the collections at Jim's Journey: The Huck Finn Freedom Center, Mark Twain Boyhood Home and Museum, or Molly Brown Museum and Home. Explore landmarks like Rockcliffe Mansion, Mark Twain Memorial Lighthouse, and Planters Barn Theater. Explore nature at Murphy Island and Sodalis Nature Preserve.