A river with a bridge, a town, and a forested hillside.

Hotels with Spa in Hannibal, Missouri

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Check availability on Hannibal Hotels with Spa

Tonight
Sep 29 - Sep 30
Tomorrow
Sep 30 - Oct 1
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Hannibal hotels with a spa

A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.
A hotel room with a bed, a sofa, a desk, and a lamp.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

1. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
  • Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
P4,797
P5,720 total
includes taxes & fees
Oct 4 - Oct 5
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
An outdoor patio with tables and chairs, green umbrellas, and string lights.
A hotel room with a sofa, armchair, lamp, and a large mirror.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.

2. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
  • Revitalizing spa treatments await at this hotel, where an indoor pool, cozy pillow menus, and attentive staff create a relaxing retreat.
P8,443
P9,624 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Quincy East by IHG
View all properties

Choose what matters most at spa hotels in Hannibal

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Hannibal Hotel Reviews

Best Western On The River

Best Western On The River

10/10 Excellent
"The hotel is sleek and modern without being fancy. The location was fantastic, the staff was very helpful, and the pool was a lovely way to start or end the day."
Sonia 1-night trip
Posted 16 hours ago
Best Western On The River
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

8/10 Good
"This was a great stop on our Mississippi River travels"
Mary 2-night trip
Posted 2 days ago
Quality Inn & Suites Hannibal West
Stoney Creek Inn Quincy

Stoney Creek Inn Quincy

10/10 Excellent
"A wonderful place for a weekend getaway with the family. Very relaxing experience."
Rachele 1-night trip
Posted 2 days ago
Stoney Creek Inn Quincy
Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

10/10 Excellent
"Good location. Nice view of the river."
Craig 1-night trip
Posted 6 days ago
Microtel Inn & Suites by Wyndham Quincy Downtown/River Area
AmericInn by Wyndham Quincy

AmericInn by Wyndham Quincy

8/10 Good
"Comfortable beds and convenient location."
Peggy 3-night trip
Posted 3 weeks ago
AmericInn by Wyndham Quincy

Frequently asked questions

Looking to vacation at a spa hotel in Hannibal?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers recommend the gourmet restaurants in Hannibal. Enjoy the shopping and riverfront during your vacation. Spa hotels are a great way to break out of your routine and add a layer of luxury to your vacation.
What is the best spa hotel in Hannibal?
Comfort Inn & Suites - Hannibal is a top spa hotel featuring a 24-hour fitness center and an indoor pool. Kick back and relax in the hot tub.
How many spa hotels are there in Hannibal?
Among Expedia's 54 accommodation options in Hannibal, there is 1 spa hotel.
What's there to see and do in Hannibal?
Take in the sights and attractions that Hannibal offers with a visit to Rockcliffe Mansion, Mark Twain Boyhood Home and Museum, and Mark Twain Memorial Lighthouse. If you have a little extra time during your trip, you might want to check out Lovers Leap and Mark Twain Cave.
What is a Hannibal spa hotel?
Spa hotels in Hannibal provide lodging and have an on-site spa offering services such as couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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