Gay friendly Hotels in Hannibal, Missouri

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Check availability on Hannibal Gay friendly Hotels

Tonight
Dec 31 - Jan 1
Tomorrow
Jan 1 - Jan 2
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Hannibal LGBT-friendly hotels

Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers
Best Western On The River

Best Western On The River

Best Western On The River
2.5 star property
Hannibal
8.6 out of 10, Excellent, (1001)
"Great stay! Clean and cozy!!"
United States
Courtney
The price is P6,002
P6,893 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Best Western On The River
Exterior
Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
3.0 star property
Quincy
8.8 out of 10, Excellent, (611)
"Overall very nice property. "
United States
Jeffrey
The price is P6,532
P7,445 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Holiday Inn Quincy East by IHG
Lobby
Fairfield Inn & Suites Quincy

Fairfield Inn & Suites Quincy

Fairfield Inn & Suites Quincy
2.5 star property
Quincy
8.6 out of 10, Excellent, (336)
"We were very pleased with our stay. The room was clean and the staff was VERY friendly. We were also VERY impressed the breakfast. We would definitely stay there again."
United States
Julie
The price is P6,453
P7,355 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Fairfield Inn & Suites Quincy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Hannibal Hotel Reviews

Frequently asked questions

Searching for an LGBTQ-friendly accommodation in Hannibal?
Consider this your open invitation to pack your bags and find LGBTQ-friendly hotels in Hannibal on Expedia. The restaurants is something travelers enjoy about this welcoming area.
What is the top LGBTQ-friendly accommodation in Hannibal?
Holiday Inn Express And Suites Hannibal - Medical Center by IHG is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Main Street Bed & Breakfast is another good choice for your trip.
How many gay-friendly accommodations are there in Hannibal?
There are currently 2 gay-friendly lodging options in Hannibal.
What should I do while I'm visiting Hannibal?
During your trip, get out and discover everything Hannibal is known for. You and your traveling companions may want to visit Rockcliffe Mansion, Mark Twain Boyhood Home and Museum, and Mark Twain Memorial Lighthouse. While you're here, create some great memories of your trip with stops at Mark Twain Cave and Cameron Cave, Mark Twain Cave, and Mississippi River.
What is a gay-friendly hotel in Hannibal?
LGBTQ-friendly hotels welcome all travelers who identify as LGBTQIA+. Expedia has compiled a selection of LGBTQ-friendly hotels worldwide. In Hannibal, these hotels will provide lesbian, gay, bisexual, and transgender adventurers with the information needed to design the trip of a lifetime.
What can I expect from a gay-friendly hotel in Hannibal?
Stay at an LGBTQ-friendly hotel in Hannibal and get a warm welcome from a community you belong to. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer wedding ceremonies and honeymoon packages for same-sex couples.

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