Guayaquil Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for Guayaquil vacation rentals

Restaurant
Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
10.0 out of 10, Exceptional, (2)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is P13,545
P15,150 total
Dec 26 - Dec 27
Hotel Río Guayas by Art Hotels Ecuador
43-inch flat-screen TV with digital channels, TV, Netflix
Luxury Suites Riverfront GYE

Aparthotel in Puerto Santa Ana

Luxury Suites Riverfront GYE
3.5 star property
9.4 out of 10, Exceptional, (100)
"The apartment was in a great location and very clean and well maintained."
United States
Rolando
The price is P6,302
P6,361 total
Jan 4 - Jan 5, 2026
Luxury Suites Riverfront GYE
Private kitchen
Suitesecu Rentals Guayaquil

Aparthotel in Simón Bolívar

Suitesecu Rentals Guayaquil
4.5 star property
9.4 out of 10, Exceptional, (8)
"You can walk to the airport."
United States
Digna
The price is P1,559
P1,941 total
Jan 4 - Jan 5, 2026
Suitesecu Rentals Guayaquil
Outdoor pool
River View suites Puerto Santa Ana gye

Apartment in Puerto Santa Ana

River View suites Puerto Santa Ana gye
3.0 star property
8.6 out of 10, Excellent, (43)
"The staff were soo nice with me and my family !! I really enjoy my stay :)"
United States
Maria
The price is P4,714
P4,772 total
Dec 26 - Dec 27
River View suites Puerto Santa Ana gye
Living area
Guayacan Apart Hotel

Aparthotel in Downtown Guayaquil

Guayacan Apart Hotel
2.0 star property
The price is P2,354
P2,354 total
Dec 26 - Dec 27
Guayacan Apart Hotel
Living area
PRAGA APARTMENTS

Apartment in Urdesa

PRAGA APARTMENTS
4.0 star property
9.0 out of 10, Wonderful, (15)
"Great place to stay at "
United States
Eric
PRAGA APARTMENTS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Guayaquil Hotel Reviews

Oro Verde Guayaquil

Oro Verde Guayaquil

10/10 Excellent
"Perfect"
CARLOS 1-night trip
Posted 2 days ago
Oro Verde Guayaquil

Find out more about Guayaquil

Search for holiday rentals in Guayaquil on Expedia! You can easily find your home rentals, villas, holiday apartments in Guayaquil using one of the methods below:

  • View our selection of featured holiday rentals in Guayaquil
  • Use the map to find apartments and other holiday homes in the Guayaquil neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Guayaquil while they last

Look no further and take a look at our great range of rental properties in Guayaquil!

Frequently asked questions

Are there vacation rentals in Guayaquil?

Yes, there are vacation rentals in Guayaquil close to Santa Ana Port, or you can choose a more secluded option if you're looking for a relaxing stay. Tourists appreciate the array of shops and the cathedral in Guayaquil. While you're here, grab a bite or have a drink at the seafood restaurants.

What are some of the best vacation rentals in Guayaquil?

Casa con Piscina Privada para Familias: Visitors like this Guayaquil vacation home rental. It is located in a shopping district and has an outdoor pool, a garden, and air-conditioning to put you at ease in your new surroundings.

How many vacation rentals will I find in Guayaquil?

Expedia has 31 vacation rentals for your stay in Guayaquil.

What can I see and do in Guayaquil?

Santa Ana Port and Parque Acuatico Puerto Hondo are a couple of family-friendly sights, whereas cultural attractions include Teatro Sanchez Aguilar and Supercines Orellana. City Mall and Mall del Sol Shopping Center are other places to visit while you're in town.

What are vacation rentals like in Guayaquil?

Vacation rentals are private accommodations you can stay in for a few days or a quick weekend in Guayaquil. Vacation rentals feature extras such as kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about cleanliness, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular option for small groups.