A lakeside marina with boats docked, surrounded by lush greenery and a golf course.

Luxury Hotels in Greenville - Spartanburg, South Carolina

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Greenville - Spartanburg Luxury Hotels

Tonight
Sep 29 - Sep 30
Tomorrow
Sep 30 - Oct 1
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Greenville - Spartanburg luxury hotels

A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.
A modern interior with a fireplace, plush seating, and a stone accent wall.
An outdoor dining area with multiple tables and chairs, large windows, and a view of greenery.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
P24,330
P27,565 total
includes taxes & fees
Oct 4 - Oct 5
Grand Bohemian Lodge Greenville, Autograph Collection
A hotel facade with arched windows, a fountain, and a sign for "The Westin."
A lobby with patterned flooring, a grand staircase, and elegant furniture.
Meeting facility
A grand lobby with a chandelier, multiple seating areas, and a checkered floor pattern.

2. The Westin Poinsett Greenville

The Westin Poinsett Greenville
Greenville Downtown
  • Historic luxury awaits in downtown Greenville, with pillowtop beds and attentive service at this architectural gem.
P10,570
P12,163 total
includes taxes & fees
Oct 18 - Oct 19
The Westin Poinsett Greenville
A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.
A modern living room with a fireplace, seating area, and a bar with shelves of bottles.
A large, two-story house with a symmetrical facade, large windows, and a central entrance.
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.

3. Hotel Hartness

Hotel Hartness
Greenville
P9,518
P12,848 total
includes taxes & fees
Oct 4 - Oct 5
Hotel Hartness
A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.
A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.
A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.
A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

4. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
Greenville Downtown
P9,069
P9,976 total
includes taxes & fees
Oct 4 - Oct 5
Mint House Greenville Downtown by Kasa
A bar area with multiple hanging decorative lights, a counter with bar stools, and a seating area with chairs.
A banquet hall with round tables set for dining, large windows, and a stage with curtains.
A spacious indoor venue with rows of white chairs adorned with purple sashes, large windows, and a modern ceiling design.
A modern building with a large illuminated logo reading "TOPGOLF" on the facade.

5. Greenville Marriott

Greenville Marriott
Greenville
P11,446
P12,968 total
includes taxes & fees
Oct 13 - Oct 14
Greenville Marriott
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A bar with a large window view of mountains and a chandelier.
A swimming pool with lounge chairs and a building with balconies.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.

6. Hotel Domestique

Hotel Domestique
Travelers Rest
P26,206
P28,827 total
includes taxes & fees
Oct 4 - Oct 5
Hotel Domestique
A modern building with outdoor seating and a garden.
A row of modern, two-story buildings with a covered patio area.
A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.
A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

7. The Station by Compo Hotels

The Station by Compo Hotels
Travelers Rest
P16,766
P23,602 total
includes taxes & fees
Oct 4 - Oct 5
The Station by Compo Hotels
Exterior
Terrace/patio
Interior
Dining

8. Bed & Breakfast on Tiffany Hill

Bed & Breakfast on Tiffany Hill
Mills River
P20,264
P22,848 total
includes taxes & fees
Oct 2 - Oct 3
Bed & Breakfast on Tiffany Hill
A lakeside view with a wooden deck and seating area overlooking the water and mountains.
A restaurant with wooden flooring, large windows with a view of a lake, and multiple tables and chairs.
A bar area with a stone wall, wooden bar counter, and multiple liquor bottles.
A rustic interior with a stone fireplace, wooden beams, and a chandelier.

9. The Lodge on Lake Lure

The Lodge on Lake Lure
Lake Lure
P17,825
P20,142 total
includes taxes & fees
Oct 4 - Oct 5
The Lodge on Lake Lure
View all properties

Top Greenville - Spartanburg Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent
"Overall very positive experience"
Kannan 1-night trip
Posted 6 hours ago
Best Western Plus Greenville I-385 Inn & Suites
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

10/10 Excellent
"Perfect"
Angela 3-night trip
Posted 1 day ago
Comfort Inn Greenville - Haywood Mall
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

8/10 Good
"The staff was lovely and the rooms were great nice comfortable bed. We had a really nice view from the window on the fifth floor. The only thing was they were doing renovations which I wasn’t expecting. Other than that everything was great."
Faviola 1-night trip
Posted 7 days ago
Hyatt Place Greenville/Haywood

Explore a world of travel with Expedia