A riverside walkway with cyclists, a bridge, and modern buildings.

Hotels with Spa in Greenville, South Carolina

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Check availability on Greenville Hotels with Spa

This weekend
Jul 3 - Jul 5
Next weekend
Jul 10 - Jul 12

Our top choices for Greenville hotels with a spa

Couples treatment rooms, body treatments, body wraps, body scrubs

Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (756 reviews)
  • cleanliness
    Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
The price is P11,522
P14,764 total
includes taxes & fees
Jul 5 - Jul 6
Hotel Hartness
Spa

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (518 reviews)
  • cleanliness
    Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
The price is P17,792
P20,105 total
includes taxes & fees
Jul 6 - Jul 7
Grand Bohemian Lodge Greenville, Autograph Collection
Desk, iron/ironing board, free cribs/infant beds, rollaway beds

Best Western Spartanburg I-26

Best Western Spartanburg I-26
2.0 star property
Spartanburg
5.6 out of 10, (354 reviews)
The price is P5,905
P6,555 total
includes taxes & fees
Jul 11 - Jul 12
Best Western Spartanburg I-26
Fountain

Hotel Domestique

Hotel Domestique
4.0 star property
Travelers Rest
9.8 out of 10, Exceptional, (33 reviews)
  • cleanliness
    Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
The price is P25,795
P28,374 total
includes taxes & fees
Jul 8 - Jul 9
Hotel Domestique
Exterior

The Orchard Inn

The Orchard Inn
3.0 star property
Saluda
9.4 out of 10, Exceptional, (140 reviews)
  • cleanliness
    Enjoy a couples massage or solo Swedish retreat in this peaceful bed & breakfast with gardens and a 24-hour gym.
The price is P18,414
P20,209 total
includes taxes & fees
Aug 3 - Aug 4
The Orchard Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Greenville

Pool
Hot tub

Top Greenville Hotel Reviews

Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

10/10 Excellent
"Very clean. Great breakfast"
Jamie 2-night trip
Posted 17 hours ago
Drury Inn & Suites Greenville

Frequently asked questions

Looking to vacation at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Grand Bohemian Lodge Greenville, Autograph Collection is a top spa hotel featuring a 24-hour fitness center and a restaurant. Enjoy a massage at The Spa at Grand Bohemian. Another popular spa hotel in Greenville is Hotel Hartness.
How many spa hotels will I find in Greenville?
Among Expedia's 683 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children's Museum of the Upstate, and Bon Secours Wellness Arena. If you have some spare time during your trip, you might want to check out Beattie House and Greenville Zoo.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas and offer services like couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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