Hotels with Spa in Florence, South Carolina

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Florence Hotels with Spa

Tonight
Jul 21 - Jul 22
Tomorrow
Jul 22 - Jul 23
This weekend
Jul 25 - Jul 27
Next weekend
Aug 1 - Aug 3

Top Florence Hotels with Spa

Hampton Inn & Suites Florence Center
Reception

Hampton Inn & Suites Florence Center

2.5 star property
9.0 out of 10, Wonderful, (759)
"Room was great, the bathroom could’ve been cleaner. The staff was excellent and super friendly, we would definitely stay again if traveling through the area."
The price is P6,320
P7,078 total
includes taxes & fees
Aug 3 - Aug 4
Hampton Inn & Suites Florence Center
Comfort Inn & Suites
Lobby

Comfort Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (1036)
"one of the nicest comfort inns ive ever been to… bed was super comfortable "
The price is P6,271
P7,024 total
includes taxes & fees
Aug 10 - Aug 11
Comfort Inn & Suites
Homewood Suites by Hilton Florence
Free daily on-the-go breakfast

Homewood Suites by Hilton Florence

3.0 star property
8.4 out of 10, Very Good, (621)
"Nice hotel, modern, great staff, large rooms"
The price is P6,028
P6,977 total
includes taxes & fees
Aug 3 - Aug 4
Homewood Suites by Hilton Florence
Comfort Suites Florence I-95
Exterior

Comfort Suites Florence I-95

2.5 star property
8.4 out of 10, Very Good, (1003)
"Clean, comfortable and great location right off I95"
The price is P5,660
P6,568 total
includes taxes & fees
Jul 28 - Jul 29
Comfort Suites Florence I-95
TownePlace Suites by Marriott Florence
Exterior

TownePlace Suites by Marriott Florence

3.0 star property
9.0 out of 10, Wonderful, (615)
"We really enjoyed our stay!"
The price is P6,360
P7,123 total
includes taxes & fees
Jul 27 - Jul 28
TownePlace Suites by Marriott Florence
Howard Johnson by Wyndham Florence
Lobby

Howard Johnson by Wyndham Florence

2.0 star property
8.8 out of 10, Excellent, (2306)
"Excellent location "
The price is P4,129
P4,625 total
includes taxes & fees
Jul 28 - Jul 29
Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC
Exterior

Park Inn by Radisson Florence, SC

2.5 star property
9.0 out of 10, Wonderful, (2098)
"Great place to stay."
The price is P5,376
P6,021 total
includes taxes & fees
Aug 17 - Aug 18
Park Inn by Radisson Florence, SC
Staybridge Suites Florence - Civic Center by IHG
Exterior

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
9.4 out of 10, Exceptional, (878)
"Enjoyed the stay "
The price is P7,492
P8,391 total
includes taxes & fees
Aug 17 - Aug 18
Staybridge Suites Florence - Civic Center by IHG
Tru by Hilton Florence I-95
Terrace/patio

Tru by Hilton Florence I-95

2.5 star property
8.2 out of 10, Very Good, (1003)
"Dog friendly and very clean!"
The price is P5,785
P6,680 total
includes taxes & fees
Aug 3 - Aug 4
Tru by Hilton Florence I-95
La Quinta Inn & Suites by Wyndham Florence
Exterior

La Quinta Inn & Suites by Wyndham Florence

3.0 star property
8.0 out of 10, Very Good, (1655)
"Great friendly place to stay"
The price is P5,491
P6,149 total
includes taxes & fees
Aug 17 - Aug 18
La Quinta Inn & Suites by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Florence Hotel Reviews

Residence Inn Marriott Florence

Residence Inn Marriott Florence

10/10 Excellent
"Overnight desk clerk, Kim, was very friendly and welcoming "
Heather 1-night trip
Posted 2 days ago
Residence Inn Marriott Florence

Frequently asked questions

Looking to vacation at a spa hotel in Florence?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Florence. Be sure to pay a visit to the museums during your stay. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, detox wrap, or Swedish massage at the onsite spa.
How many spa hotels are there in Florence?
Among Expedia's 99 accommodation options in Florence, there is 1 spa hotel.
What's there to see and do in Florence?
Enjoy all that Florence has to offer when you visit Florence Museum, Florence National Cemetery, and Magnolia Mall. If you have extra time while you're in the area, you might want to see Florence Veterans Park and Florence Civic Center.
What is a Florence spa hotel?
Spa hotels in Florence provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.