East Main Street Hotels near Grand Junction
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for East Main Street hotels
Dtwn Walkability! Grand Junction Couple's Retreat
Dtwn Walkability! Grand Junction Couple's RetreatEast Main Street
10.0 out of 10, Exceptional, (3 reviews)
"Our stay was fantastic! The location was perfect—close to everything. The property was clean and loved the decor. The host was super responsive and helpful, making our trip stress-free. Highly recommend!"
renee
The price is P5,511
P15,874 total
includes taxes & fees
Apr 5 - Apr 6
Balanced Rock Inn
Balanced Rock Inn19 km from East Main Street
9.2 out of 10, Wonderful, (34 reviews)
"Clean and recently remodeled. Friendly staff as well. Check in was quick and easy. "
Donald
The price is P4,796
P5,480 total
includes taxes & fees
Apr 8 - Apr 9
Best Western Grande River Inn & Suites
Best Western Grande River Inn & Suites8.7 km from East Main Street
8.8 out of 10, Excellent, (824 reviews)
"Was pleasantly surprised by this hotel! Just passing through and needed a quick overnight stay and found this hotel to be comfortable, quaint, and clean! Breakfast was wonderful and had an adorable courtyard. "
Kari
The price is P5,611
P5,962 total
includes taxes & fees
Apr 6 - Apr 7
La Quinta Inn & Suites by Wyndham Fruita
La Quinta Inn & Suites by Wyndham Fruita18.8 km from East Main Street
8.4 out of 10, Very Good, (1,009 reviews)
"Clean room, friendly staff, good coffee"
Amy
The price is P5,611
P6,411 total
includes taxes & fees
Apr 6 - Apr 7
Wine Country Inn Palisade
Wine Country Inn Palisade17.1 km from East Main Street
9.6 out of 10, Exceptional, (1,003 reviews)
"lovely stay in palisade, CO. Charming hotel, nicely done and not like the chain properties. easy to get to and close to the many winery and vineyards in the area. "
Tammy
The price is P9,756
P10,828 total
includes taxes & fees
Apr 1 - Apr 2
Spoke and Vine Motel
Spoke and Vine Motel17.4 km from East Main Street
9.8 out of 10, Exceptional, (167 reviews)
"What a great hotel! They have done a fantastic job with upgrades to the rooms and facilities. The staff was super friendly. Highly recommend this hidden gem. "
Russ
The price is P9,756
P10,828 total
includes taxes & fees
Apr 6 - Apr 7
The Homestead
The Homestead20.4 km from East Main Street
10.0 out of 10, Exceptional, (66 reviews)
"Very beautiful setting in a cute town famed for its Palisade Peaches!"
Ronald
The price is P12,281
P12,928 total
includes taxes & fees
Apr 6 - Apr 7
Castle Creek B&B
Castle Creek B&B3.4 km from East Main Street
9.8 out of 10, Exceptional, (214 reviews)
"This place was so cozy and the staff was incredibly friendly. The breakfast that they served was delicious and the quiche was out of this world. I’m definitely coming back!"
Ethan
The price is P9,003
P10,323 total
includes taxes & fees
Apr 1 - Apr 2
Ramada by Wyndham Grand Junction
Ramada by Wyndham Grand JunctionHorizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very Good, (1,898 reviews)
"The hotel was dated for the interior but it was clean and comfortable."
Tina
The price is P4,633
P5,312 total
includes taxes & fees
Apr 13 - Apr 14
Grand Vista Hotel
Grand Vista HotelHorizon Drive District, 5.5 km from East Main Street
8.2 out of 10, Very Good, (3,553 reviews)
"Definitely would stay here again."
Joe
The price is P4,306
P4,937 total
includes taxes & fees
Apr 1 - Apr 2
Tru by Hilton Grand Junction Downtown
Tru by Hilton Grand Junction DowntownHistoric Grand Junction, 1.4 km from East Main Street
9.2 out of 10, Wonderful, (1,008 reviews)
"Perfect location. Walkable to restaurants and bars."
Christy
The price is P6,068
P6,958 total
includes taxes & fees
Apr 19 - Apr 20
The Hotel Melrose
The Hotel MelroseHistoric Grand Junction, 1.3 km from East Main Street
9.0 out of 10, Wonderful, (138 reviews)
"Clean room"
Brian
The price is P11,554
P13,248 total
includes taxes & fees
Apr 7 - Apr 8
Hampton Inn Grand Junction Downtown/Historic Main Street
Hampton Inn Grand Junction Downtown/Historic Main StreetHistoric Grand Junction, 1.5 km from East Main Street
8.8 out of 10, Excellent, (1,001 reviews)
"Great location & breakfast."
Susan
The price is P7,020
P8,049 total
includes taxes & fees
Apr 5 - Apr 6
La Quinta Inn & Suites by Wyndham Grand Junction
La Quinta Inn & Suites by Wyndham Grand JunctionHorizon Drive District, 5.4 km from East Main Street
8.8 out of 10, Excellent, (2,868 reviews)
"nice room, very friendly staff, overall nice stay"
Cosette
The price is P4,864
P5,578 total
includes taxes & fees
Apr 5 - Apr 6
Home2 Suites by Hilton Grand Junction Northwest
Home2 Suites by Hilton Grand Junction Northwest24 Road Corridor, 5.8 km from East Main Street
9.2 out of 10, Wonderful, (925 reviews)
"Great staff and location"
Juancarlos
The price is P8,858
P10,157 total
includes taxes & fees
Apr 5 - Apr 6
Comfort Inn & Suites Fruita - Grand Junction
Comfort Inn & Suites Fruita - Grand Junction18.5 km from East Main Street
8.4 out of 10, Very Good, (1,006 reviews)
"The property was clean, rooms were clean, staff was helpful
Pool and surrounding area could have used some attention (cleaning)"
Christina
The price is P5,253
P6,002 total
includes taxes & fees
Apr 26 - Apr 27
Super 8 by Wyndham Fruita
Super 8 by Wyndham Fruita18.6 km from East Main Street
8.4 out of 10, Very Good, (1,000 reviews)
"Loved our dog friendly room. Easy access to a grassy park. Will come back again. "
Tara
The price is P4,190
P4,788 total
includes taxes & fees
Apr 16 - Apr 17
Doubletree Hotel Grand Junction
Doubletree Hotel Grand JunctionHorizon Drive District, 5 km from East Main Street
8.2 out of 10, Very Good, (1,003 reviews)
"Love this place"
Alejandra
The price is P6,654
P7,629 total
includes taxes & fees
Apr 8 - Apr 9
Quality Inn Grand Junction near University
Quality Inn Grand Junction near UniversityHorizon Drive District, 4.9 km from East Main Street
8.6 out of 10, Excellent, (1,006 reviews)
"Great value and perfect for our business trip."
Damon
The price is P5,087
P5,832 total
includes taxes & fees
Apr 5 - Apr 6
Clarion Inn Grand Junction
Clarion Inn Grand JunctionHorizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very Good, (1,726 reviews)
"The staff was amazing!!!"
Mary Ellen
The price is P5,481
P6,285 total
includes taxes & fees
Apr 5 - Apr 6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in East Main Street
Find the best East Main Street areas and neighborhoods for the activities you enjoy most.
Redlands
You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.
Downtown
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.
Pear Park
If you're spending some time in Pear Park, Colorado River and James M. Robb – Colorado River State Park are top sights worth seeing.
Historic Grand Junction
Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.
Horizon Drive District
While there might not be top attractions in Horizon Drive District, you can explore the larger area and discover places like Grand Junction Motor Speedway and Canyon View Park.
Top East Main Street Hotel Reviews
Holiday Inn & Suites Grand Junction by IHG
10/10 Excellent
