Downtown Hotels near Seneca

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 19 - Nov 20
Tomorrow
Nov 20 - Nov 21
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Downtown, Seneca

Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 star property
Downtown
8.0 out of 10, Very Good, (659)
"Friendly check in, clean room."
United States
connie
The price is P4,460
P5,261 total
includes taxes & fees
Dec 7 - Dec 8
Quality Inn Seneca Clemson Area US-123
Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 star property
8.3 km from Downtown
9.2 out of 10, Wonderful, (781)
"Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!"
United States
Gretchen
The price is P5,616
P6,178 total
includes taxes & fees
Dec 12 - Dec 13
Tru by Hilton Seneca Clemson
Desk, free cribs/infant beds, rollaway beds, free WiFi
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
3.1 km from Downtown
6.8 out of 10, (714)
"The rooms have been renovated it was nice and clean especially for the price. "
United States
Sherri
The price is P4,112
P4,523 total
includes taxes & fees
Nov 25 - Nov 26
Days Inn by Wyndham Seneca / Clemson Area
Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1004)
"Overall great stay."
United States
Daniel
The price is P6,423
P7,973 total
includes taxes & fees
Nov 24 - Nov 25
Lakeside Lodge Clemson
Property amenity
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
11.8 km from Downtown
8.2 out of 10, Very Good, (1000)
" Clean room, breakfast, staff very nice."
United States
Maria Claudia
The price is P4,964
P5,511 total
includes taxes & fees
Nov 23 - Nov 24
Best Western Plus Clemson Hotel & Conference Center
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
2 km from Downtown
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
The price is P7,079
P7,787 total
includes taxes & fees
Nov 24 - Nov 25
Fairfield Inn & Suites Seneca Clemson Univ Area
Lobby
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 star property
11.7 km from Downtown
8.2 out of 10, Very Good, (1000)
"Great stay "
United States
Linda
The price is P5,616
P6,234 total
includes taxes & fees
Nov 26 - Nov 27
Comfort Inn & Suites Clemson - University Area
Lobby lounge
Inn @ Clemson

Inn @ Clemson

2.5 star property
11.6 km from Downtown
8.0 out of 10, Very Good, (1006)
"Very nice staff and great place to stay"
United States
Kimberley
The price is P11,150
P12,377 total
includes taxes & fees
Nov 21 - Nov 22
Inn @ Clemson
Exterior
Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85

2.5 star property
25.4 km from Downtown
7.4 out of 10, Good, (54)
"Room was wonderful. Employees were on point "
United States
Daniel
The price is P5,244
P5,821 total
includes taxes & fees
Nov 24 - Nov 25
Woodspring Suites Anderson North I-85
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (46)
"The place was absolutely magnificent."
United States
David
The price is P5,251
P8,371 total
includes taxes & fees
Nov 20 - Nov 21
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Reception
Quality Inn Clemson near University

Quality Inn Clemson near University

2.5 star property
29.6 km from Downtown
7.0 out of 10, Good, (886)
"Bueno was "
Mexico
Alejandro
The price is P3,212
P3,565 total
includes taxes & fees
Nov 30 - Dec 1
Quality Inn Clemson near University
In-room safe, blackout drapes, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (727)
"Wonderful staff, great location"
United States
Shelly
The price is P9,970
P11,067 total
includes taxes & fees
Dec 7 - Dec 8
The Shepherd Hotel Downtown Clemson
Outdoor pool
Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

2.5 star property
25 km from Downtown
7.0 out of 10, Good, (832)
"Clean attractive room and friendly staff. "
Canada
Lisa
The price is P3,506
P3,892 total
includes taxes & fees
Dec 1 - Dec 2
Baymont by Wyndham Anderson Clemson
Exterior
Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
2.2 km from Downtown
9.2 out of 10, Wonderful, (655)
"Great place to stay"
United States
Jose
The price is P6,088
P6,697 total
includes taxes & fees
Dec 14 - Dec 15
Hampton Inn & Suites Seneca-Clemson Area
View from property
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (956)
"Great place to stay!"
United States
Mindi
The price is P8,790
P9,757 total
includes taxes & fees
Nov 20 - Nov 21
Clemson University's James F. Martin Inn
Gazebo
Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson

3.5 star property
12.5 km from Downtown
6.8 out of 10, (195)
"Rooms were clean. Check in was easy. TV and AC both worked great. Conveniently located to dining and shopping options. No issues or complaints. Would stay again. "
United States
Sean
The price is P4,463
P4,954 total
includes taxes & fees
Nov 23 - Nov 24
Days Inn by Wyndham Clemson
Fireplace
Courtyard Marriott Clemson

Courtyard Marriott Clemson

3.0 star property
12.9 km from Downtown
9.0 out of 10, Wonderful, (522)
"Excellent!!! We loved everything about it!!! "
United States
Sarah
The price is P6,849
P7,603 total
includes taxes & fees
Nov 29 - Nov 30
Courtyard Marriott Clemson
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
24.8 km from Downtown
8.2 out of 10, Very Good, (1002)
"Room was clean, staff was nice! "
United States
Martina
The price is P4,708
P5,226 total
includes taxes & fees
Nov 24 - Nov 25
Microtel Inn & Suites by Wyndham Anderson/Clemson
Lobby
Best Western Seneca-Clemson

Best Western Seneca-Clemson

2.5 star property
1.7 km from Downtown
8.4 out of 10, Very Good, (632)
"Convenient for Clemson visits."
United States
Kathleen
The price is P5,466
P6,012 total
includes taxes & fees
Nov 26 - Nov 27
Best Western Seneca-Clemson
Reception
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
25 km from Downtown
9.0 out of 10, Wonderful, (578)
"It was great. Room was clean and staff was friendly. "
United States
Veronica
The price is P6,069
P6,737 total
includes taxes & fees
Nov 30 - Dec 1
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and World of Energy are some notable places to visit nearby.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like The Gauntlet and Seneca Historic District.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to The Gauntlet and Seneca Historic District, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

10/10 Excellent
"Was very clean and quiet. Staff were very nice. "
Sunny 3-night trip
Posted 2 days ago
Days Inn by Wyndham Anderson

Explore a world of travel with Expedia

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Seneca Historic District and The Gauntlet as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on Expedia customer reviews, Quality Inn Seneca Clemson Area US-123 is the highest ranked property in Downtown. This hotel offers free breakfast and free parking.
How many hotels can I expect to find in Downtown?
Expedia has 9 Downtown hotels and other accommodations, and one might make a good home base for venturing out into the greater Seneca area.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
What can I see and do in this Seneca neighborhood?
Seneca Historic District, The Gauntlet, and Bertha Lee Strickland Cultural Museum are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Oconee County Library Seneca Branch and Seneca City Hall are some other places worth a visit. Golden Corner Plaza, Oconee Community Theatre, and Applewood Shopping Center are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Wyndham Plaza or Cross Creek Plantation Golf.