Hotels near Colleton Medical Center

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Our top choices for Colleton Medical Center hotels

Free daily on-the-go breakfast
Sleep Inn Walterboro I-95

Sleep Inn Walterboro I-95

Sleep Inn Walterboro I-95
2.5 star property
2 km from Colleton Medical Center
7.6 out of 10, Good, (575)
"Very clean rooms and super friendly staff."
United States
henry
The price is P4,944
P5,537 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Sleep Inn Walterboro I-95
Desk, free WiFi
Southern Inn By OYO Walterboro I-95

Southern Inn By OYO Walterboro I-95

Southern Inn By OYO Walterboro I-95
2.5 star property
1.8 km from Colleton Medical Center
7.0 out of 10, Good, (82)
"Room is badly overrated. Sink was clogged. Interior badly needs remodeled."
United States
Ronnie
The price is P2,718
P3,367 total
includes taxes & fees
Dec 28 - Dec 29
Southern Inn By OYO Walterboro I-95
Front of property - evening/night
Travelodge by Wyndham Walterboro

Travelodge by Wyndham Walterboro

Travelodge by Wyndham Walterboro
2.0 star property
1.8 km from Colleton Medical Center
6.2 out of 10, (530)
"Everything is ok "
United States
Fonda
The price is P3,231
P3,619 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Travelodge by Wyndham Walterboro
Exterior
Super 8 by Wyndham Walterboro

Super 8 by Wyndham Walterboro

Super 8 by Wyndham Walterboro
2.0 star property
2.3 km from Colleton Medical Center
6.2 out of 10, (211)
"Stay was good. "
United States
Cindy
The price is P3,446
P3,859 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Super 8 by Wyndham Walterboro
Premium bedding, desk, soundproofing, iron/ironing board
Red Roof Inn Walterboro

Red Roof Inn Walterboro

Red Roof Inn Walterboro
2.0 star property
6.1 km from Colleton Medical Center
6.6 out of 10, (863)
"Always stay here on our way to the mountains "
United States
Judy
The price is P3,201
P3,585 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Red Roof Inn Walterboro
Front of property - evening/night
Baymont by Wyndham Walterboro

Baymont by Wyndham Walterboro

Baymont by Wyndham Walterboro
2.5 star property
6.2 km from Colleton Medical Center
6.2 out of 10, (1044)
"I like the quietness. "
United States
Joseph
The price is P2,908
P3,257 total
includes taxes & fees
Dec 28 - Dec 29
Baymont by Wyndham Walterboro
Free daily buffet breakfast
Hampton Inn & Suites Walterboro

Hampton Inn & Suites Walterboro

Hampton Inn & Suites Walterboro
2.5 star property
6.9 km from Colleton Medical Center
9.2 out of 10, Wonderful, (1004)
"Wonderful stay!"
United States
Efrain
The price is P9,436
P10,568 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Hampton Inn & Suites Walterboro
Desk, iron/ironing board, free WiFi, bed sheets
Comfort Inn & Suites Walterboro I-95

Comfort Inn & Suites Walterboro I-95

Comfort Inn & Suites Walterboro I-95
2.5 star property
6.6 km from Colleton Medical Center
8.6 out of 10, Excellent, (1003)
"Room is clean and staff was very courteous and check in was a breeze. Would stay here again"
United States
Teddy
The price is P6,337
P7,097 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Comfort Inn & Suites Walterboro I-95
Breakfast area
Econo Lodge Walterboro I-95

Econo Lodge Walterboro I-95

Econo Lodge Walterboro I-95
2.0 star property
5.9 km from Colleton Medical Center
7.8 out of 10, Good, (1001)
"Great motel and great prices "
United States
Kent
The price is P3,067
P3,435 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Econo Lodge Walterboro I-95
Free daily buffet breakfast
Holiday Inn Exp Walterboro by IHG

Holiday Inn Exp Walterboro by IHG

Holiday Inn Exp Walterboro by IHG
2.5 star property
6.8 km from Colleton Medical Center
8.6 out of 10, Excellent, (1002)
"Big room and friendly staff. Breakfast was great "
United States
Michael
The price is P7,931
P8,883 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Holiday Inn Exp Walterboro by IHG
Free WiFi, bed sheets
Motel 6 Walterboro, SC

Motel 6 Walterboro, SC

Motel 6 Walterboro, SC
2.0 star property
6.6 km from Colleton Medical Center
8.2 out of 10, Very Good, (1420)
"Room was spotless and the staff was excellent. Would love to stay here again. "
United States
Tina
The price is P3,278
P3,671 total
includes taxes & fees
Dec 29 - Dec 30
Motel 6 Walterboro, SC
Lobby
Best Western Of Walterboro

Best Western Of Walterboro

Best Western Of Walterboro
2.5 star property
6.3 km from Colleton Medical Center
7.6 out of 10, Good, (341)
"Room was very clean and quiet. Easy check in and check out. "
United States
Jessica
The price is P4,758
P5,329 total
includes taxes & fees
Dec 29 - Dec 30
Best Western Of Walterboro
Exterior
Microtel Inn & Suites by Wyndham Walterboro

Microtel Inn & Suites by Wyndham Walterboro

Microtel Inn & Suites by Wyndham Walterboro
2.0 star property
6.9 km from Colleton Medical Center
8.0 out of 10, Very Good, (1004)
"Definitely a good place to stay along your travels on I-95"
United States
Larry
The price is P5,542
P6,207 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Microtel Inn & Suites by Wyndham Walterboro
Free daily buffet breakfast
Quality Inn Walterboro I-95

Quality Inn Walterboro I-95

Quality Inn Walterboro I-95
2.5 star property
6.8 km from Colleton Medical Center
7.6 out of 10, Good, (865)
"It was so nice we booked additional week. "
United States
R
The price is P4,130
P4,626 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Quality Inn Walterboro I-95
Room amenity
Rodeway Inn Walterboro I-95

Rodeway Inn Walterboro I-95

Rodeway Inn Walterboro I-95
2.0 star property
6.4 km from Colleton Medical Center
7.0 out of 10, Good, (260)
"The AC worked hgreat, .my room was clean and the staff was friendly. "
United States
Tammy
The price is P2,746
P3,076 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Rodeway Inn Walterboro I-95
Lobby
Days Inn by Wyndham Walterboro

Days Inn by Wyndham Walterboro

Days Inn by Wyndham Walterboro
2.0 star property
6.8 km from Colleton Medical Center
7.2 out of 10, Good, (767)
"It was just ok"
United States
Julie
The price is P3,696
P4,139 total
includes taxes & fees
Dec 29 - Dec 30
Days Inn by Wyndham Walterboro
Reception
Budgetel

Budgetel

Budgetel
2.0 star property
6 km from Colleton Medical Center
3.6 out of 10, (5)
"There was bedbugs! Tim was very friendly though. "
United States
Abu
The price is P4,112
P4,606 total
includes taxes & fees
Dec 28 - Dec 29
Budgetel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Colleton Medical Center Hotel Reviews

Econo Lodge

Econo Lodge

10/10 Excellent
"Room was clean. We didn't use breakfast which was very basic. But there was coffee machine which was grinding and making decent coffee. "
Alexander 1-night trip
Posted 6 days ago
Econo Lodge

Hotels near other Colleton Medical Center attractions

First Baptist Church

3.9/5 (30 reviews)
After visiting First Baptist Church, make a plan to see the other sights and activities in Walterboro. While you're here, you can savor the top-notch restaurants.
See properties

Forest Hills Tennis Center

Catch an event at Forest Hills Tennis Center during your trip to Walterboro. While you're here, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Colleton Medical Center?
Colleton Medical Center is located in Walterboro. This welcoming area is known for its array of dining options. You'll find 39 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Colleton Medical Center?
Baymont by Wyndham Walterboro is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3.9 mi (6.2 km) from Colleton Medical Center. Other good choices within a few miles include Comfort Inn & Suites Walterboro I-95 and Motel 6 Walterboro, SC.
How many hotels will I be able to find close to Colleton Medical Center?
Expedia has 39 hotels and other accommodations a few miles from Colleton Medical Center.
If I need to cancel the hotel reservation for my stay near Colleton Medical Center, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals available near Colleton Medical Center.