Photo by Alice Andersen

Gay friendly Hotels in Clarksdale, Mississippi

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Clarksdale Gay friendly Hotels

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Clarksdale LGBT-friendly hotels

Reception
Hampton Inn Clarksdale

Hampton Inn Clarksdale

Hampton Inn Clarksdale
2.5 star property
Clarksdale
8.2 out of 10, Very Good, (333)
"We would stay there again."
United States
Andrew Ray
The price is P7,972
P8,690 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hampton Inn Clarksdale
Rooftop bar
Cotton House, Cleveland, a Tribute Portfolio Hotel

Cotton House, Cleveland, a Tribute Portfolio Hotel

Cotton House, Cleveland, a Tribute Portfolio Hotel
3.5 star property
Cleveland
9.0 out of 10, Wonderful, (622)
"I enjoyed my stay."
United States
Janeka
The price is P9,236
P10,067 total
includes taxes & fees
Dec 30 - Dec 31
Cotton House, Cleveland, a Tribute Portfolio Hotel
Free buffet breakfast
Holiday Inn Express Hotel & Suites Cleveland by IHG

Holiday Inn Express Hotel & Suites Cleveland by IHG

Holiday Inn Express Hotel & Suites Cleveland by IHG
2.5 star property
Cleveland
7.8 out of 10, Good, (937)
"Roaches in the room. Hotel under construction "
United States
GEORGE
The price is P6,647
P7,246 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Holiday Inn Express Hotel & Suites Cleveland by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Clarksdale Hotel Reviews

Frequently asked questions

How do I find an LGBTQ-friendly hotel in Clarksdale?
Consider this your open invitation to pack your bags and find gay-friendly hotels in Clarksdale on Expedia. Visitors are sure to enjoy all Clarksdale has to offer including its restaurants.
What is the favorite LGBTQ-friendly hotel in Clarksdale?
Hampton Inn Clarksdale is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi.
What should I see while I'm in Clarksdale?
During your vacation, get out and enjoy everything Clarksdale has to offer. You and your traveling companions may want to visit Delta Blues Museum, Ground Zero Blues Club, and Mississippi River. While you're here, create some great memories of your trip with stops at New Roxy, Red's Lounge, and Hambone Art Gallery.
What is a gay-friendly hotel in Clarksdale?
LGBTQ-friendly hotels welcome all travelers who identify as LGBTQIA+. You'll find a selection of LGBTQ-friendly accommodations on our site. In Clarksdale, these hotels will provide lesbian, gay, bisexual, and transgender adventurers with the information needed to design the trip of a lifetime.
What can I expect from an LGBTQ-friendly accommodation in Clarksdale?
Take a vacation from the ordinary; stay at a gay-friendly hotel in Clarksdale, and you'll be around like-minded people, so you can relax and enjoy your trip. Many of our LGBTQ-friendly accommodations offer wedding ceremonies and honeymoon packages for same-sex couples.

Explore a world of travel with Expedia