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Cherokee Seneca Hotels near Louisville

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Check prices for these dates

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

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Our top choices for Cherokee Seneca hotels

Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay "
United States
Jedediah
The price is P7,459
P8,776 total
includes taxes & fees
Dec 27 - Dec 28
Hyatt Regency Louisville
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 6.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (3883)
"Great place to stay! "
United States
Rochelle
The price is P7,829
P9,212 total
includes taxes & fees
Dec 30 - Dec 31
Galt House Hotel Trademark Collection by Wyndham
Free daily buffet breakfast
SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 5.9 km from Cherokee Seneca
8.4 out of 10, Very Good, (1002)
"The staff was great and the hotel was really nice. Great place to stay."
United States
James
The price is P5,462
P6,427 total
includes taxes & fees
Dec 28 - Dec 29
SpringHill Suites by Marriott Louisville Downtown
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 5.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1000)
"The staff and lobby were top tier!"
United States
Emily
The price is P5,600
P6,589 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Cambria Hotel Louisville Downtown-Whiskey Row
View from room
Aloft Louisville Downtown

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 6.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1000)
"Great room and location."
Canada
Rene
The price is P5,912
P6,956 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Aloft Louisville Downtown
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1665)
"very clean throughout, helpful staff,very nice breakfast"
United States
Wayne
The price is P4,824
P5,676 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express & Suites Louisville Downtown by IHG
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, 7 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1001)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is P8,164
P9,899 total
includes taxes & fees
Jan 1 - Jan 2, 2026
21c Museum Hotel Louisville
Premium bedding, in-room safe, desk, laptop workspace
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1716)
"Great place to stay"
United States
april
Derby City Gaming & Hotel - A Churchill Downs Property
Terrace/patio
Hyatt House Louisville East

Hyatt House Louisville East

Hyatt House Louisville East
2.0 star property
9.2 km from Cherokee Seneca
9.6 out of 10, Exceptional, (1001)
"The hotel was very clean and the decor is appealing."
United States
Erika L
The price is P6,402
P7,532 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt House Louisville East
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1122)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is P7,176
P8,443 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Embassy Suites Louisville Downtown
Exterior
Fairfield Inn & Suites by Marriott Louisville Shepherdsville

Fairfield Inn & Suites by Marriott Louisville Shepherdsville

Fairfield Inn & Suites by Marriott Louisville Shepherdsville
2.5 star property
19.2 km from Cherokee Seneca
9.4 out of 10, Exceptional, (409)
"Breakfast was good"
United States
Chantal
The price is P5,462
P6,079 total
includes taxes & fees
Dec 30 - Dec 31
Fairfield Inn & Suites by Marriott Louisville Shepherdsville
Snack bar
Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South
2.5 star property
19.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (840)
"Excellent service from check in to check out highly recommend very clean "
United States
Rebecca
The price is P4,768
P5,307 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Tru by Hilton Shepherdsville Louisville South
Exterior
Marriott Louisville East

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown, 9.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1001)
"Very nice hotel, rooms were clean and comfortable, breakfast is great!"
United States
Miguel
The price is P6,440
P7,577 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Marriott Louisville East
Lobby
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (517)
"Accommodations were perfect. Staff excellent. Food was very good."
United States
Bennett
The price is P5,697
P6,703 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Towneplace Suites By Marriott Louisville Downtown
Exterior
Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport
3.0 star property
7.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (342)
"Amenities, restaurants, location, room was nice "
United States
Anitra
The price is P5,756
P6,772 total
includes taxes & fees
Dec 29 - Dec 30
Courtyard by Marriott Louisville Airport
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.6 out of 10, Excellent, (1002)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is P8,396
P9,879 total
includes taxes & fees
Dec 30 - Dec 31
Seelbach Hilton Louisville Downtown
Exterior
Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
2.5 star property
Downtown Louisville, 6 km from Cherokee Seneca
8.4 out of 10, Very Good, (1001)
"Friendly staff, clean room, breakfast was good"
United States
steven
The price is P4,941
P5,814 total
includes taxes & fees
Dec 30 - Dec 31
Fairfield Inn & Suites by Marriott Louisville Downtown
Exterior
Holiday Inn Express Hotel & Suites Louisville East by IHG

Holiday Inn Express Hotel & Suites Louisville East by IHG

Holiday Inn Express Hotel & Suites Louisville East by IHG
2.5 star property
Jeffersontown, 13.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (758)
"Very good breakfast and friendly staff. The room very spacious and very clean"
United States
Khanh
The price is P4,875
P5,736 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Holiday Inn Express Hotel & Suites Louisville East by IHG
Free daily on-the-go breakfast
Hampton Inn Simpsonville

Hampton Inn Simpsonville

Hampton Inn Simpsonville
2.5 star property
29.6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (904)
"Would stay again"
United States
Chris
The price is P5,249
P5,843 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn Simpsonville
Exterior
Comfort Suites Louisville Airport

Comfort Suites Louisville Airport

Comfort Suites Louisville Airport
2.5 star property
9.5 km from Cherokee Seneca
8.2 out of 10, Very Good, (864)
"The room was clean, front desk people were so polite! "
United States
Sara
The price is P5,300
P6,236 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas and neighborhoods for the activities you enjoy most.
Louisville which includes signage and street scenes as well as a small group of people

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Conrad Caldwell House showing signage and heritage elements

Old Louisville

Old Louisville is known for its abundant dining options, and you can plan a trip to Ohio River Valley and Conrad-Caldwell House Museum while you're in town.

Top Cherokee Seneca Hotel Reviews

The Brown Hotel

The Brown Hotel

10/10 Excellent
"All of the above! Love the bars, the gift shop, and the Hot Brown!"
Scott 2-night trip
Posted 2 days ago
The Brown Hotel

Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun visiting Louisville's Cherokee Seneca neighborhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to review top deals in Cherokee Seneca.
What is there to do around this Louisville neighborhood?
Peterson-Dumesnil House, Historic Frankfort Avenue, and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.

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