A large white dome building with a red brick base, surrounded by green trees and a clear blue sky.

Hotels with Spa in Central Missouri, Missouri

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Central Missouri Hotels with Spa

Tonight
Oct 8 - Oct 9
Tomorrow
Oct 9 - Oct 10
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Central Missouri hotels with a spa

A lakeside bar named "FIRE ICE" with outdoor seating and a view of the lake.
A spacious lobby with a high ceiling, stone accents, and a central fireplace.
An outdoor seating area with a fire pit, chairs, and a view of a lake at sunset.
A lobby with a stone fireplace, seating area, and a view of the sky through the ceiling.

1. Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa
Lake Ozark
  • Luxurious lakeside retreat with rejuvenating spa treatments and tranquil Japanese gardens for ultimate relaxation.
P5,228
P7,150 total
includes taxes & fees
Nov 1 - Nov 2
Lodge Of Four Seasons Golf Resort, Marina & Spa
A hotel room with two beds, a nightstand, a cabinet, and a wall-mounted artwork.
An aerial view of a marina at dusk with illuminated buildings, docks, and boats.
A poolside area with stone walls and a bar.
A marina with docks and a large hotel building in the background.

2. Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
Lake Ozark
  • Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.
P5,312
P8,126 total
includes taxes & fees
Nov 1 - Nov 2
Camden on the Lake Resort & Spa
A thatched-roof building with a sign reading "TIKI HUT POOL BAR".
A waterfront view with a dock, a marina, and a building with balconies overlooking the water.
Two people sitting on green Adirondack chairs facing a body of water with a forested shoreline in the background.
A deck with a view of a lake, dock, and chairs.

3. Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
Osage Beach
  • Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.
P9,038
P10,985 total
includes taxes & fees
Nov 1 - Nov 2
Margaritaville Lake Resort Lake of the Ozarks
A bar area with wooden counters and stone accents, a stone wall, and a wooden door.
A stone gazebo with a stone pathway leading to it, surrounded by well-maintained grass and a pond.
A balcony with two chairs and a table, overlooking a golf course and a lake.
A golf course with a swimming pool and a clubhouse.

4. The Lodge at Old Kinderhook Golf Resort

The Lodge at Old Kinderhook Golf Resort
Camdenton
  • Revitalize at this lakeside retreat with full-service spa, golf course, and dual pools for ultimate relaxation.
P8,418
P10,010 total
includes taxes & fees
Oct 26 - Oct 27
The Lodge at Old Kinderhook Golf Resort
A room with a bed, a desk with a computer, and a shelf with toiletries.
A historic Courtyard Hotel with large windows, a brick facade, and a welcoming entrance.
A dining area with a large wooden table and ornate chairs, a ceiling fan, and framed artwork on the walls.
A room with a large window, a ceiling fan, a sofa, a table with chairs, and a lamp.

5. The Courtland Hotel and Day Spa

The Courtland Hotel and Day Spa
Fort Scott
  • Tranquil historic hotel offers rejuvenating spa escape with four serene treatment rooms for ultimate relaxation.
P5,398
P6,242 total
includes taxes & fees
Oct 20 - Oct 21
The Courtland Hotel and Day Spa
A spa area with a massage table, a hot tub, and a grill.
A hot tub, a fire pit, and a view of a lake.
A living room with a fireplace, a dining area with a round table, and a balcony with a view.
A row of houses with a driveway leading to a gated entrance.

6. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
P20,696
P23,795 total
includes taxes & fees
Nov 2 - Nov 3
Hermann Hill
View all properties

Choose what matters most at spa hotels in Central Missouri

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Central Missouri Hotel Reviews

Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

10/10 Excellent
"We enjoyed our family stay in July. Lots of things for everyone in the family to do. The pools got very busy and we're hard to find a place to enjoy, but throughout the rest of the stay there was plenty that kept everyone happy! The painting class was super fun, we had drinks at several bars, food at Fin City and Landsharks, went bowling, visited the gym, used the indoor hot tub, played in the arcade, had brunch with mimosa, and just enjoyed our weekend. We will definitely be back!"
Heather 3-night trip
Posted 10 hours ago
Margaritaville Lake Resort Lake of the Ozarks
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

10/10 Excellent
"Everything was clean and staff was friendly. Enjoyed the pool and hot tub. Good variety free breakfast. Only two issues, toilet didn't always flush properly and there was no coffee to fix a cup to go on my way out at checkout."
Linda 2-night trip
Posted 11 hours ago
Wingate by Wyndham - Columbia
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

10/10 Excellent
"Excellent bfst"
Ronald 1-night trip
Posted 16 hours ago
Country Inn & Suites by Radisson, Columbia, MO

Explore a world of travel with Expedia