Reserving a rental car for your escape to Madrid is a cinch with Expedia. Around 2 kilometers from Monumento a Santiago Ramón y Cajal, Enterprise is one of multiple car rental companies located in the area. Also take a look at the rates at Budget and Hertz. Even if you need a set of wheels today, you can key in your pick-up and drop-off locations to view amazing deals from a wide variety of providers. Pick the one that best suits your style, or click on the "Great Deal" filter for more exclusive prices.