Cairo Hotels

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Our top choices for Cairo hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (275)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
The price is P4,668
P5,181 total
includes taxes & fees
Feb 7 - Feb 8
Quality Inn Cairo I-57

La Center Motel

La Center Motel
2.0 star property
La Center
7.8 out of 10, Good, (17)
"Quiet and convenient."
United States
Alma
La Center Motel

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (618)
"Staff was great! Room was nice. "
United States
Lana
The price is P3,671
P4,073 total
includes taxes & fees
Jan 15 - Jan 16
Super 8 by Wyndham Charleston/Sikeston East MO

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
"Middle of nowhere hotel was ok"
United States
David
The price is P3,575
P3,968 total
includes taxes & fees
Jan 8 - Jan 9
Eagle Inn Charleston

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is P7,152
P17,139 total
includes taxes & fees
Jan 16 - Jan 17
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Cairo attractions

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town.

Cairo Ohio River Bridge traversing over the Ohio River at sunset

Top Cairo Hotel Reviews

More cheap stays in Cairo

Find out more about Cairo

Top reasons to visit Cairo

  • Scenic Outdoor Activities: Cairo offers beautiful recreational areas, perfect for hiking, camping, and enjoying nature.
  • Rich Cultural Experience: Explore local shops and indulge in the vibrant atmosphere that reflects Cairo's unique history.
  • Romantic Getaways: Ideal for couples, Cairo provides picturesque settings for a memorable escape.
  • Convenient Accommodation: A variety of lodging options cater to all types of travellers, ensuring a comfortable stay.
  • Proximity to National Parks: Discover nearby wildlife preserves and parks for an adventurous day out.

Find great hotels in and around Cairo

Discover a range of delightful accommodation options in Cairo, Illinois, catering to every type of traveller. From family-friendly hotels to pet-friendly lodgings, you’ll find the perfect spot for your stay. Whether you seek a business travel experience or a relaxing vacation, Cairo’s hotels offer essential amenities and warm hospitality. Explore the best hotels in the area and read reviews to ensure an enjoyable stay in this charming town.

  • Super 8 by Wyndham Charleston/Sikeston East MO: This family-friendly motel offers a welcoming atmosphere for those travelling with children and pets. Located a short drive from Cairo, it’s designed for a wholesome vacation experience. Guests appreciate the thoughtful amenities for children, including complimentary cribs when reserved in advance. The property is also pet-friendly, allowing pets on-site, which makes it a great choice for families who want to keep their furry companions close. Enjoy the convenience of a comfortable stay with a warm, homely vibe at Super 8.
  • Quality Inn Charleston - Sikeston: Perfect for business travellers, this hotel strikes a balance between work and leisure. Situated slightly further from Cairo, it offers essential amenities for a productive stay, alongside pet-friendly policies. The hotel permits pets with certain restrictions, ensuring that your furry friends are accommodated as well. Guests can enjoy a comfortable room equipped with modern conveniences, making it a reliable choice for those on business trips or leisure visits alike.
  • Quality Inn Cairo I-57: Located right in Cairo, this hotel provides a perfect blend of family and pet-friendly accommodations. With thoughtful amenities such as a free crib for infants and a first aid kit, it caters to families seeking comfort and safety. The property allows dogs and has specific policies in place to ensure a pleasant stay for both guests and their pets. Quality Inn Cairo I-57 is an ideal choice for travellers looking to create lasting memories with their loved ones.

Where to stay near Cairo

Cairo, Illinois, offers a delightful blend of outdoor scenery and rich history, perfect for a romantic getaway or family-friendly adventure. Explore charming local shops and savour the warm weather while immersing yourself in the vibrant atmosphere. Nearby towns provide additional cultural insights, ensuring a well-rounded experience. Discover the best places to relax and unwind, making your visit to Cairo truly memorable.

  • Wickliffe: Situated a mere 9.7km from Cairo, Wickliffe offers a delightful escape for those seeking outdoor adventures and scenic beauty. The city is known for its recreational areas and well-maintained golf courses, making it a perfect spot for both relaxation and activity. Visitors can explore the nearby national park, lush forests, and tranquil lakes that surround the area, providing ample opportunities for hiking, picnicking, and enjoying nature. The best times to visit are from March to April and August, when the weather is ideal for outdoor pursuits.
  • Mound City: Also located 9.7km from Cairo, Mound City is a charming destination that shares a similar appeal with Wickliffe. Known for its outdoor activities, visitors flock here for the breathtaking scenery and various recreational opportunities, including golf and exploration of nearby natural landscapes. The city is surrounded by a national park, forests, and lakes, making it an excellent choice for nature lovers. Peak visiting times occur in March, July, and October, offering vibrant experiences in line with the region's seasonal changes.
  • Wyatt: Positioned 11.3km from Cairo, Wyatt is a family-friendly city that combines urban charm with outdoor activities. The city features recreational areas, adventure activities, and golf, catering to families and those seeking a lively city experience. With its urban parks and serene lakes, Wyatt is an ideal destination for leisurely strolls or engaging in fun-filled family activities. The summer months from June to August are particularly popular, providing warm weather and an array of outdoor events for visitors to enjoy.

Things to do near Cairo

Cairo, Illinois, is ideal for outdoor enthusiasts and those seeking romantic escapes, offering activities such as scenic recreational areas, golf courses, and riverboat tours. Visitors can enjoy weekend getaways and camping sites, alongside a variety of indoor activities. The charm of Cairo lies in its picturesque settings, making it perfect for exploring and unwinding amidst nature.

Shopping

Cairo offers a quaint shopping experience with local shops and markets. For more extensive options, head to the nearby Cape Girardeau Mall, featuring a variety of retail stores. If you're up for a drive, check out the bustling West Park Mall in Jackson for even more shopping delights.

Recreation

Experience rejuvenation at eDen Spa & Salon, located 45.1km from Cairo. Indulge in their body treatment services that embody wellness and relaxation, creating a tranquil atmosphere perfect for unwinding after a day of exploration.

Adventure

Embark on the Limekin Springs Trail for a scenic hike, immersing yourself in the breathtaking natural beauty 32.2km from Cairo. Alternatively, enjoy a splash at Cape Splash Family Aquatic Center, a thrilling waterpark 49.9km away, perfect for family fun and adventure.

Nightlife

Experience the vibrant nightlife at the Riverfront Grill, where you can enjoy delectable cuisine and scenic views of the Mississippi River. For a lively atmosphere, visit the Cairo Nightclub for dancing and local DJs spinning tunes that keep the energy high into the early hours.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Cairo

To save money during your visit to Cairo, Illinois, plan your trip between November and January for lower accommodation rates, particularly on Tuesdays, which are the cheapest days to stay. Use Expedia to compare prices and find eco-friendly hotels by applying relevant filters. Consider booking packages that include flights and activities for better deals. Additionally, take advantage of public transport options and explore free local attractions to further stretch your budget. Avoid visiting during peak months like April to May and August to maximise your savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Cairo are November to January, where the prices are slightly lower. This is in comparison to April to May and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Cairo is Tuesday. The most expensive day to stay in Cairo is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to tailor your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the “Eco-certified” filter will showcase sustainable and eco-friendly hotels currently available. To find the most affordable prices and deals, arrange the price filter from low to high.
  • Consider bundling your trip: You can save money by combining your hotel accommodation in Cairo with your flights and activities through an Expedia package deal.

Find the best attractions in and around Cairo

For a delightful getaway, Cairo offers a blend of outdoor activities and scenic beauty, perfect for romantic vacations. Explore the nearby national parks and wildlife preserves, or attend events at local conference venues. Visitors can immerse themselves in the rich culture and picturesque landscapes, ensuring a memorable experience. Don't miss the chance to discover the charm of Cairo itself and its surrounding attractions, which promise to enchant travellers seeking a unique escape.

  • Fort Defiance State Park: This historic site offers a glimpse into the past with its cultural vibes. Visitors can explore the remnants of the fort and enjoy picturesque views where the Mississippi and Ohio Rivers converge, making it a perfect spot for history enthusiasts.
  • Ballard Wildlife Management Area: Located 8.0km from Cairo, this reserve is a haven for birdwatchers and nature lovers. It boasts rich historical significance and budget-friendly outdoor activities, allowing you to immerse yourself in the serene landscapes and diverse wildlife.
  • Columbus-Belmont State Park: Situated 27.4km away, this national park is ideal for outdoor adventures. With stunning scenery and recreational opportunities like hiking and fishing, it provides an exhilarating experience surrounded by nature's beauty.

Best time to go to Cairo

The best time to visit Cairo can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Cairo falls in July, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Cairo falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January35.2°F (1.8°C)Light RainMostly SunnyModerately LowSlightly Low
February38.5°F (3.6°C)Light RainMostly SunnyModerately LowAverage
March48.7°F (9.3°C)Light RainMostly SunnyModerately HighAverage
April57.7°F (14.3°C)Light RainMostly SunnyModerately HighSlightly High
May67.5°F (19.7°C)Light RainMostly SunnyAverageSlightly High
June76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
July79.0°F (26.1°C)Light RainMostly SunnyAverageAverage
August77.2°F (25.1°C)Light RainMostly SunnyModerately HighSlightly High
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
November47.8°F (8.8°C)Light RainMostly SunnyModerately LowSlightly Low
December40.6°F (4.8°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Cairo

Flying into Cairo, Illinois, can be conveniently achieved via several nearby airports. Paducah, KY (PAH-Barkley Regional) is situated 37.0km away; notable hotels include The Respite Bed and Breakfast, Harrah's Metropolis Hotel & Casino, and Drury Inn Paducah, all within a short drive. Marion, IL (MWA-Williamson County Regional), located 83.7km from Cairo, offers accommodations such as Drury Inn & Suites Marion and Holiday Inn Carbondale-Conference Center. Cape Girardeau, MO (CGI-Cape Girardeau Municipal), is 41.8km away, with options like Drury Plaza Hotel Cape Girardeau and Pear Tree Inn Cape Girardeau. Each airport provides access to various transport services for easy travel to your chosen hotel.

Frequently asked questions

Where is the best place for a stay in Cairo?
Based on our traveler data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your trip to the area are Super 8 by Wyndham Charleston/Sikeston East MO and Quality Inn Charleston - Sikeston. See all available top hotels, or vacation rentals in Cairo.
If I need to cancel my hotel reservation in Cairo, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.
What is staying in Cairo like?
Visitors can enjoy all that Cairo has to offer including the restaurants, entertainment choices, and riverfront. This city also attracts tourists with its small-town vibe. There are 27 hotels and other accommodations in the surrounding area. Find out more about Cairo.
What should I see while I'm in Cairo?
The picturesque setting of Mississippi River and Ohio River Valley exemplify the area's natural beauty. Additionally, you might want to add Fort Defiance State Park to your itinerary. Check out what more to see and do in Expedia's Cairo guide.
What's the seasonal weather like in Cairo?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.

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