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Cairo Hotels

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Aug 25 - Aug 26
Tomorrow
Aug 26 - Aug 27
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

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Our top choices for Cairo hotels

1. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
P4,443
P4,931 total
includes taxes & fees
Aug 31 - Sep 1
Quality Inn Cairo I-57

2. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
France
P3,672
P4,075 total
includes taxes & fees
Aug 30 - Aug 31
Super 8 by Wyndham Charleston/Sikeston East MO

3. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Bobby
P4,103
P4,553 total
includes taxes & fees
Sep 7 - Sep 8
The Riverstone Hotel Charleston-Sikeston

4. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
P4,751
P5,273 total
includes taxes & fees
Aug 26 - Aug 27
Eagle Inn Charleston

5. La Center Motel

La Center Motel
La Center
United States
Carrie
P2,999
P3,541 total
includes taxes & fees
Sep 20 - Sep 21
La Center Motel

6. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
Cunningham
P9,195
P17,926 total
includes taxes & fees
Sep 23 - Sep 24
Quiet Country Stay: Modern Home Near Paducah
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Stay near popular Cairo attractions

Fort Defiance State Park

7.4/10 (15 reviews)
Where the mighty Mississippi and Ohio rivers converge, Fort Defiance Park offers a rare view of this natural phenomenon. Explore the historic grounds where Lewis and Clark once trained the Corps of Discovery in 1803.
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Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artifacts from this once-thriving river port town.

See all hotels in Cairo
A steel bridge with a sunset in the background.

Top Cairo Hotel Reviews

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent
"Nice staff. Very accommodating."
Domingo 1-night trip
Posted 2 weeks ago
Super 8 by Wyndham Charleston/Sikeston East MO
La Center Motel

La Center Motel

10/10 Excellent
"Great AC unit in the room!"
Jonathan 1-night trip
Posted 2 weeks ago
La Center Motel
Eagle Inn Charleston

Eagle Inn Charleston

10/10 Excellent
"Great"
Jackson 1-night trip
Posted 5 months ago
Eagle Inn Charleston

More cheap stays in Cairo

La Center Motel

La Center Motel

474 W Kentucky Dr La Center KY
P2,999
P3,541 total
Sep 20 - Sep 21
includes taxes & fees
7.6/10 Good! (22 reviews)
La Center Motel
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO
P3,672
P4,075 total
Aug 30 - Aug 31
includes taxes & fees
Super 8 by Wyndham Charleston/Sikeston East MO
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

102 Drake St Charleston MO
P4,103
P4,553 total
Sep 7 - Sep 8
includes taxes & fees
The Riverstone Hotel Charleston-Sikeston
Quality Inn Cairo I-57

Quality Inn Cairo I-57

13201 Kessler Road Cairo IL
P4,443
P4,931 total
Aug 31 - Sep 1
includes taxes & fees
6.4/10 (293 reviews)
Quality Inn Cairo I-57
Eagle Inn Charleston

Eagle Inn Charleston

2811 East Marshall Street Charleston MO
P4,751
P5,273 total
Aug 26 - Aug 27
includes taxes & fees
6.6/10 (106 reviews)
Eagle Inn Charleston

Find out more about Cairo

Top reasons to visit Cairo

  • Scenic Riverboat Tours: Experience the area's beautiful waterways through unique riverboat tours, offering stunning views and a relaxing adventure.
  • Outdoor Recreation: Enjoy camping and various outdoor activities in the picturesque parks and nature reserves surrounding Cairo.
  • Rich Historical Charm: Explore Cairo's streets and uncover its fascinating history, reflected in local architecture and culture.
  • Family-Friendly Atmosphere: Experience a welcoming community vibe, perfect for families and visitors of all backgrounds.
  • Varied Accommodation: Choose from a range of delightful lodgings, including pet-friendly hotels and charming inns, catering to diverse needs.

Find great hotels in and around Cairo

Discover delightful hotel accommodation options in Cairo, Illinois, where you'll find a range of lodgings to suit every traveller. From pet-friendly hotels to welcoming inns, Cairo offers a charming experience for families and LGBTQIA visitors alike. Whether you're seeking agritourism properties or convenient motels, you'll find the perfect place to rest after exploring this unique destination.

  • Super 8 by Wyndham Charleston/Sikeston East MO: This budget-friendly motel offers a welcoming atmosphere for families and pet owners alike. Located 16km from Cairo, it features amenities designed for a comfortable family stay, including complimentary cribs for infants, ensuring your little ones have everything they need. The Super 8 also accommodates pets, making it an excellent choice for those who wish to travel with their furry companions. Guests can enjoy a range of services, including a convenient location for exploring the nearby attractions.
  • The Riverstone Hotel Charleston-Sikeston: Situated 19km from Cairo, The Riverstone Hotel caters to both business travellers and pet owners. Its budget-friendly rates and practical amenities make it an attractive option for those on the go. The hotel provides a pet-friendly environment, with specific provisions for dogs, ensuring that your four-legged friends are well taken care of. With a focus on comfort and convenience, the Riverstone Hotel is an excellent base for business trips or leisurely explorations of the surrounding areas.
  • Quality Inn Cairo I-57: Located within Cairo, the Quality Inn offers a budget-friendly stay with a family-oriented approach. The hotel features amenities for children, including free cribs and a first aid kit for added peace of mind. Pet owners will appreciate the accommodating policies, allowing for dogs and providing necessary amenities. The Quality Inn ensures a comfortable experience with easy access to local attractions, perfect for families and pet owners seeking a welcoming environment.

Where to stay near Cairo

For an unforgettable vacation, Cairo, Illinois, offers a unique blend of outdoor adventures and historical charm. Stroll through the scenic streets of Cairo, where family-friendly vibes and local culture come to life. Explore nearby campgrounds for a taste of nature, or delve into the rich history of the area. With its welcoming atmosphere, Cairo is perfect for those seeking both relaxation and exploration during their holidays.

  • Wickliffe: Situated a mere 10km from Cairo, Wickliffe is a charming city known for its picturesque outdoor settings. This destination draws visitors not only for its scenic beauty but also for romantic escapes amidst nature. Popular activities include golfing and exploring the expansive recreational areas. Nature enthusiasts can enjoy local landmarks such as the national state park and tranquil lakes, making Wickliffe an ideal spot for those looking to unwind while soaking in the stunning environment.
  • Mound City: Also just 10km from Cairo, Mound City offers an adventurous spirit for tourists seeking outdoor thrills and romantic outings. With peaks in visitor numbers during March, July, and October, there's a steady stream of travellers drawn to its recreational parks and lush forests. The local lakes provide a perfect backdrop for various activities, allowing guests to connect with nature while enjoying the facilities for golfing and relaxation. Mound City is a delightful place to explore the beauty of the outdoors.
  • Wyatt: Located 11km from Cairo, Wyatt is a vibrant city that caters to families and outdoor enthusiasts alike. Popular during the summer months, Wyatt offers a variety of activities, including golf and visits to the dog park. The urban parks serve as excellent venues for family outings and community events, ensuring that there’s always something happening. With its charming parks and event conference venues, Wyatt presents a blend of city life and family-friendly experiences that are sure to delight visitors.

Things to do in Cairo

Shopping

Cairo offers quaint local shops for unique souvenirs, such as the Cairo Museum Gift Shop. For a broader selection, if you're up for a drive, visit the nearby West Park Mall in Cape Girardeau, which features various retail chains and dining options.

Recreation

In Cairo, Illinois, the Riverfront Wellness Centre offers various fitness classes and relaxation therapies, allowing you to rejuvenate while enjoying scenic views of the Mississippi River. Nearby, the scenic trails at Fort Defiance State Park provide opportunities for peaceful walks and nature exploration, enhancing your wellness experience.

Adventure

In Cairo, explore the scenic trails of the Mississippi River, ideal for hiking and birdwatching. The nearby Fort Defiance Park offers stunning views where the Ohio and Mississippi rivers meet, perfect for picnics and leisurely walks in nature, immersing you in the local landscape and wildlife.

Nightlife

Cairo, Illinois, offers a quaint nightlife scene with venues like the Riverfront Bar & Grill, where live music and hearty meals set a lively atmosphere. The nearby local pubs provide a relaxed vibe, perfect for unwinding with friends over drinks and conversation.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Cairo

To save money during your visit to Cairo, Illinois, plan your trip between November and January for lower accommodation rates, particularly on Tuesdays, which are the cheapest days to stay. Use Expedia to compare prices and find eco-friendly hotels by applying relevant filters. Consider booking packages that include flights and activities for better deals. Additionally, take advantage of public transport options and explore free local attractions to further stretch your budget. Avoid visiting during peak months like April to May and August to maximise your savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Cairo are November to January, where the prices are slightly lower. This is in comparison to April to May and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Cairo is Tuesday. The most expensive day to stay in Cairo is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to tailor your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the “Eco-certified” filter will showcase sustainable and eco-friendly hotels currently available. To find the most affordable prices and deals, arrange the price filter from low to high.
  • Consider bundling your trip: You can save money by combining your hotel accommodation in Cairo with your flights and activities through an Expedia package deal.

Find the best attractions in and around Cairo

Cairo offers a delightful escape for those seeking outdoor adventures and scenic beauty. Visitors can explore various attractions, including national and state parks, nature reserves, and historic forts. These points of interest provide a rich cultural experience alongside opportunities for outdoor activities, making Cairo an ideal destination for travellers looking to immerse themselves in nature and history.

  • Columbus-Belmont State Park: Located 27km from Cairo, this state park offers stunning outdoor scenery and adventurous activities. Visitors can explore hiking trails, enjoy picnicking spots, and take in the views of the Mississippi River, making it an ideal locale for nature enthusiasts.
  • Ballard Wildlife Management Area: Just 8km away, this wildlife preserve provides a serene escape with its rich historical background. It’s a budget-friendly destination for birdwatching and appreciating the local flora and fauna while learning about the area's ecological significance.
  • Fort Defiance State Park: Situated within Cairo, this historic fort immerses visitors in local culture. It features interpretive trails and scenic overlooks, allowing guests to learn about the region's history and enjoy picturesque views of the confluence of the Mississippi and Ohio rivers.

Best time to go to Cairo

The best time to visit Cairo is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January35.2°F (1.8°C)Light RainMostly SunnyModerately LowSlightly Low
February38.5°F (3.6°C)Light RainMostly SunnyModerately LowAverage
March48.7°F (9.3°C)Light RainMostly SunnyModerately HighSlightly High
April57.7°F (14.3°C)Light RainMostly SunnyModerately HighSlightly High
May67.5°F (19.7°C)Light RainMostly SunnyAverageSlightly High
June76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
July79.0°F (26.1°C)Light RainMostly SunnyAverageAverage
August77.2°F (25.1°C)Light RainMostly SunnyModerately HighAverage
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
November47.8°F (8.8°C)Light RainMostly SunnyModerately LowSlightly Low
December40.6°F (4.8°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Cairo

Accessing Cairo, Illinois, is convenient via nearby airports. Cape Girardeau Municipal Airport (CGI) is 42km away, with several hotels such as Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown, both around 10km from the airport. Barkley Regional Airport in Paducah, KY, is 37km from Cairo, offering accommodations like The Respite Bed and Breakfast, 14km away. Finally, Veterans Airport of Southern Illinois (MWA) is 84km distant, featuring hotels like Drury Inn & Suites Marion, just 3km from the airport. Each airport provides accessible transport options to ensure a smooth journey to Cairo.

Frequently asked questions

Where is the best place for a stay in Cairo?
Based on our traveler data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your trip to the area are Super 8 by Wyndham Charleston/Sikeston East MO and The Riverstone Hotel Charleston-Sikeston. See all available top hotels, or vacation rentals in Cairo.
If I need to cancel my hotel reservation in Cairo, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.
What is staying in Cairo like?
Visitors can enjoy all that Cairo has to offer including the restaurants, entertainment choices, and riverfront. This city also attracts tourists with its small-town vibe. There are 27 hotels and other accommodations in the surrounding area. Find out more about Cairo.
What should I see while I'm in Cairo?
The picturesque setting of Mississippi River and Ohio River Valley exemplify the area's natural beauty. Additionally, you might want to add Fort Defiance State Park to your itinerary. Check out what more to see and do in Expedia's Cairo guide.
What's the seasonal weather like in Cairo?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.

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