- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Samos Prefecture 5-star hotels

2. Proteas Blu Resort - Adults Only
Proteas Blu Resort - Adults OnlySamos
9.6 out of 10, Exceptional, (122 reviews)

4. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)Samos














