São Francisco Trips (flight + hotel)

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Where to stay in São Francisco

Find the best São Francisco areas and neighborhoods for the activities you enjoy most. Learn more about São Francisco
San Pedro de Atacama featuring a lake or waterhole, tranquil scenes and landscape views

Central North

You'll enjoy the waterfalls and riverfront in Central North. You might want to make time for a stop at Bom Jesus de Cuiaba Church or Cine Teatro Cuiaba.

Find hotels in Central North

Top hotels in São Francisco

Amazon Aeroporto Hotel

Amazon Aeroporto Hotel

3 out of 5
Avenida Governador Joao Ponce de Arruda, 50, Varzea Grande, Mato Grosso
Fully refundableReserve now, pay when you stay
The price is P5,254 per night from Aug 3 to Aug 4
P5,254
P5,517 total
Aug 3 - Aug 4
includes taxes & fees
9.4/10 Exceptional! (545 reviews)
"Walking distance from the airport but hotel also provides shuttle. Beautifully decorated lobby. All places in the hotel were spotless. Staff was professional and friendly."

Reviewed on Jul 11, 2025

Amazon Aeroporto Hotel
Delmond Hotel

Delmond Hotel

4 out of 5
Av. Andre Antonio Maggi, 1980, Alvorada, Cuiabá, MT
Fully refundableReserve now, pay when you stay
The price is P3,342 per night from Jul 26 to Jul 27
P3,342
P3,787 total
Jul 26 - Jul 27
includes taxes & fees
9/10 Wonderful! (692 reviews)
"Great place for business."

Reviewed on May 31, 2025

Delmond Hotel
Mato Grosso Palace Hotel

Mato Grosso Palace Hotel

3 out of 5
Rua Joaquim Murtinho, 170, Cuiabá, MT
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (503 reviews)
"Helpful stuff and good breakfast"

Reviewed on Jul 2, 2025

Get rates
Mato Grosso Palace Hotel
See all 116 properties in São Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a São Francisco vacation package cost?
We make it simple to explore the world, with São Francisco vacation packages starting from just . You'll have the flexibility to combine your favorite hotels, airlines and car rental. For the ultimate getaway, why not add a few tours and experiences to your itinerary?
How do I get a cheap travel package to São Francisco?
If you love getting a great deal, combine your bookings into a São Francisco vacation package. Whether you're chasing flights, hotels, tours or rental cars, you can browse and book them all in one place. You'll have ample choice at your fingertips too. Expedia has more than 550 airlines and 1,000,000 properties globally to choose from. Fly with who you prefer, stay where you like and save a tidy sum — now that's the ideal getaway!
Where should I stay in São Francisco?
If you're itching to be in the heart of the action, stay close to Arena Pantanal. Many happy campers book a hotel around this top tourist attraction.
How far in advance should I book my São Francisco vacation?
Search Expedia to compare international fares as early as possible. You can usually purchase a seat up to 12 months in advance. If you don't see your preferred air carrier, or you've left things to the last minute, don't despair. Low prices to São Francisco occasionally appear a few weeks before departure.
What does an Expedia São Francisco travel package include?
You can choose from any combination of hotels, flights and rental cars. Once you've made your booking, you can add tours and experiences. Want to pick your airfare class? That's easy to do too. The choice is yours when it comes to putting together your perfect São Francisco getaway.
What should I know before booking a São Francisco travel package?
You can save a tidy sum by bundling your hotels, flights and rental cars. Once you've made your booking, you can add on sightseeing tours or experiences. Your next unforgettable adventure is only a couple of clicks away.
Can I choose my airline with a São Francisco Expedia vacation package?
Yes — that's one of the best things about an Expedia vacation package. You can pick and choose your flights, hotels and more. We have access to more than 550 airline partners throughout the world, so you have loads of choice when creating your São Francisco escape.
If I'm not able to travel, can I cancel my São Francisco vacation package?
We totally get that life can throw you the odd curveball. If you've locked in a São Francisco vacation package and have to amend or cancel it, we can help. We recommend browsing our Customer Service Portal first for information. But generally, if you've taken out your package within 24 hours, you may be able to change your itinerary free of charge. If it's more than 24 hours, your hotel, airline or car rental company may impose a charge.

Popular places to visit

Arena Pantanal

Catch an event at Arena Pantanal during your trip to Cuiabá. Stroll along the riverfront or experience the area's museums.

Arena Pantanal

Antonio Pires de Campos Park

Explore the great outdoors at Antonio Pires de Campos Park, a lovely green space in Cuiabá. Stroll along the riverfront or experience the area's museums.

Antonio Pires de Campos Park

Ze Bolo Flo Park

Explore the great outdoors at Ze Bolo Flo Park, a lovely green space in Cuiabá. Discover the waterfalls while you're in the area.

Ze Bolo Flo Park

Things to do

8 Days Jaguars and Pantanal Safari tour

8 Days Jaguars and Pantanal Safari tour

P296,196
per adult
8 Days Jaguars and Pantanal Safari tour
See all activities in Cuiabá
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.