Santa Fe Trips (flight + hotel)

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to P 3,118 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santa Fe

Find the best Santa Fe areas and neighborhoods for the activities you enjoy most. Learn more about Santa Fe
El Castillo Museum showing heritage architecture and chateau or palace

El Poblado

6 out of top 10 points of interest in this area

Travelers love El Poblado for its popular shops, and you can see more of Medellín by jumping on the metro at Poblado Station or Aguacatala Station. You might spend time checking out top sights like Golden Mile and Oviedo Shopping Center.

Find hotels in El Poblado

Top hotels in Santa Fe

Heiss Hotel

Heiss Hotel

4 out of 5
1460 Cra. 43F, Medellín, Antioquia
Fully refundable
9/10 Wonderful! (656 reviews)
"Room clean"

Reviewed on Jul 19, 2025

Get rates
Heiss Hotel
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66, Laureles, Medellín
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (1,549 reviews)
"Location Cleanliness Staff"

Reviewed on Jul 12, 2025

Get rates
Hotel Dorado La 70
York Luxury Suites Medellín

York Luxury Suites Medellín

4 out of 5
Carrera 43a 17sur 63, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
9.4/10 Exceptional! (1,246 reviews)
"The service, food, and views were spectacular!"

Reviewed on Jul 18, 2025

Get rates
York Luxury Suites Medellín
See all 4,293 properties in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Fe vacation package cost?
Starting from as little as , you can tailor make your Santa Fe vacation package. Simply bundle flights, hotels and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Santa Fe?
Booking a flight and hotel together with Expedia won't just save precious time — it'll save you cash too. A Santa Fe vacation package makes it easy to put together the ideal trip. With more than 550 airlines across the world to pick from, finding flights that fit your schedule won't be a hassle. In addition to that, we've got over 1,000,000 properties globally to choose from. Now that's what we call choice. Whatever your budget, Expedia will help show you the world.
Where should I stay in Santa Fe?
Vacationers come from near and far to see Atanasio Giradot Stadium and Botero Plaza in Santa Fe. Stay within a stone's throw of these wonderful attractions and visit them whenever you please.
What are the top hotels in Santa Fe?
Hostel Ventura and La Palmera In Medellin are two of the most sought-after properties in Santa Fe. Why not check out the amenities and facilities at each and then decide?
How far in advance should I book my Santa Fe vacation?
It depends on the air carrier, but you can usually browse through international airfares on Expedia nearly a year in advance. While it's generally recommended to book ahead of time, lucky customers occasionally score a cheaper seat only weeks before departure dates.
What does an Expedia Santa Fe travel package include?
Car rentals, flights and hotels — we connect you to all the best deals. All you have to do is pick and choose your preferred combination. Once you've made your booking, you can add on the fun stuff like tours and experiences. Our travel packages make it easy to put together an unforgettable Santa Fe trip.
What should I know before booking a Santa Fe travel package?
Booking all the parts of your trip together is a simple way to save. Bundle your flights, car rentals and hotels into a neat little package. But you're not limited to hotels. Expedia offers all types of properties, including vacation rentals such as mountain cabins and short-term homes. Your choices are almost endless!
Can I choose my airline with a Santa Fe Expedia vacation package?
Yes, you're in control. We have access to over 550 airlines all over the world, so you can tailor your Santa Fe adventure according to your budget and style.
If I'm not able to travel, can I cancel my Santa Fe vacation package?
Because we know life can throw you a few curveballs, the answer is yes. For further details, visit our Customer Service Portal. But generally speaking, if you've booked your Santa Fe vacation package in the last 24 hours, you may be able to cancel or change it with no penalties. Your airline, hotel or car rental company may charge a fee if you made your booking a while ago.

Popular places to visit

Santafé Mall

Santafé Mall

During your visit to Medellín, you can search for that perfect souvenir at Santafé Mall. Check out the top-notch restaurants or lively bars in this walkable area.

Santafé Mall
Pueblito Paisa featuring religious aspects and a church or cathedral

Pueblito Paisa

Take a trip back in time to a replica of a typical old town from the region with a stunning view of the new city.

Pueblito Paisa

El Tesoro Shopping Park

During your visit to Medellín, you can find the perfect gifts to bring home at El Tesoro Shopping Park. Check out the top-notch restaurants or lively bars in this walkable area.

El Tesoro Shopping Park

Things to do

Queer Graffiti Private Tour

Queer Graffiti Private Tour

P14,095
per adult
Queer Graffiti Private Tour
Pablo Escobar Tour Medellin

Pablo Escobar Tour Medellin

P2,255
per adult
88% of travellers recommend
Pablo Escobar Tour Medellin
See all activities in Medellin
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.