Beginning of main content
Trip Type

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in San Francisco

Tonight Tonight Jun 24 - Jun 25
This weekend This weekend Jun 29 - Jul 1
Next weekend Next weekend Jul 6 - Jul 8

Featured San Francisco Business Hotels

See all 501 Properties in San Francisco
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.2 out of 5 (4,870 reviews)
Spacious room near fishers' wharfThis hotel has water machine in each floor. You can fill water using the bottle provided near the machine. Nice and clean neighborhood.
Jun 14, 2018
Pullman San Francisco Bay

Pullman San Francisco Bay

223 Twin Dolphin Dr, Redwood City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.2 out of 5 (2,975 reviews)
Impressive facility: clean, neat, nice, convenientI just did a "quick grab" of the options looking for a low-cost bargain. The hotel turned our to be really nice: very high standard and hence a happy surprise for my wife and I !
Jun 20, 2018
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (4,074 reviews)
Excellent hotel. Good location for tourists. Polite helpful staff. Excellent breakfast options.
Jun 13, 2018
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.0 out of 5 (8,753 reviews)
nice hotel in good locationI have stayed here a few times and I had good experience every time. The hotel is very clean. The staff are nice. The location is super convenient, right next to Union Square (just turn right as you exit the hotel on O'Farrell. Turning left leads you to the Tenderloin, which I do not recommend for ...
Jun 19, 2018
Stanford Court San Francisco

Stanford Court San Francisco

905 California Street, San Francisco
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.1 out of 5 (3,545 reviews)
Beautiful views, gorgeous locationNestled on Nob Hill, the Stanford is perfectly located. Whether traveling for business or pleasure, the location is an easy stroll downtown, and tons of great places to eat all around. The room was spacious and beautiful; well decorated, and given that it was June, it was artfully decked out for ...
Jun 21, 2018
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
  • Free Cancellation
  • Reserve now, pay when you stay
 
 
4.4 out of 5 (3,484 reviews)
Great locationStayed here for 5 nights and really enjoyed the location and room. Close to cable car line, Chinatown, Union Square. Great front desk staff, and bar area was fantastic. Only wish they had a pool. Would stay here again.
Jun 8, 2018
InterContinental San Francisco

InterContinental San Francisco

888 Howard Street, San Francisco
  • Free Cancellation
  • Reserve now, pay when you stay
4.5 out of 5.0
 
 
4.5 out of 5 (2,021 reviews)
City Centre Oasis4 night stay, with 2 kids. Friendly welcoming staff (free teddy for the youngest!), impressive foyer, comfy seats. Clean bedroom - a little tired decor in places but nothing off-putting. Lovely comfortable beds and pillows. Bathroom modern, with all facilities - mirror light not working but not major. ...
Jun 6, 2018
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.0 out of 5 (3,428 reviews)
Wow, this was unexpectedThis Hyatt was a an upscale hotel for the a reasonable price. would totally stay here again!!
Jun 10, 2018
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (3,448 reviews)
Ideal!Location was perfect, price was reasonable. Our vacation was exactly what we all needed and Hyatt Regency was a big factor in making it perfect for us. The accomodations -- breakfast buffet and night caps in the evening kept us quite comfortable. Just a short walk to the Ferry building or a short ...
Jun 18, 2018
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
  • Free Cancellation
  • Reserve now, pay when you stay
3.5 out of 5.0
 
 
3.2 out of 5 (8,805 reviews)
Old but niceIn an older section of San Fran, walking from this hotel to sights, shopping, etc. is quick but requires going through blocks where homeless people live, so that's not ideal. The hotel itself is old but kept up pretty well. The beds are comfy but there's no cable, no HD TV, and no hot water at nights. ...
Jun 19, 2018
Map

Recently booked San Francisco hotels

Hotel Zeppelin San Francisco
4.0 out of 5.0
Last booking: 42 hours ago
USA Hostels San Francisco
2.0 out of 5.0
Last booking: 42 hours ago
Marriott Courtyard San Francisco Downtown
3.5 out of 5.0
Last booking: 42 hours ago
The Marina Inn on San Francisco Bay
2.5 out of 5.0
Last booking: 42 hours ago
Orchard Hotel
4.0 out of 5.0
Last booking: 42 hours ago
Parc 55 San Francisco - A Hilton Hotel
4.0 out of 5.0
Last booking: 42 hours ago
Hotel Zephyr
3.5 out of 5.0
Last booking: 42 hours ago
Comfort Inn and Suites San Francisco Airport North
2.0 out of 5.0
Last booking: 42 hours ago
Hotel Spero
4.0 out of 5.0
Last booking: 42 hours ago

Business Hotels in San Francisco

Search for Business Hotels in San Francisco on Expedia. You can easily find your hotels in San Francisco using one of the methods below:

  • View our selection of featured hotels in San Francisco
  • Use the map to find hotels in the San Francisco neighborhood you prefer
  • Use the filters to see hotels in a specific area of San Francisco, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in San Francisco
  • Enter your travel dates to view the best deals on hotels in San Francisco - while they last